Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2195374..2195645 Replicon chromosome
Accession NZ_AP022049
Organism Escherichia coli strain WP4-S17-ESBL-08

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2195504..2195607 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2195374..2195645 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H7R14_RS10345 2191929..2192591 - 663 WP_000944256.1 exodeoxyribonuclease X -
H7R14_RS10350 2192615..2193271 - 657 WP_000011653.1 carbon-nitrogen hydrolase family protein -
H7R14_RS10355 2193373..2193603 - 231 WP_000916763.1 DNA polymerase III subunit theta -
H7R14_RS10360 2193742..2194116 + 375 WP_000168747.1 CopC domain-containing protein YobA -
H7R14_RS10365 2194120..2194992 + 873 WP_001551232.1 copper homeostasis membrane protein CopD -
H7R14_RS10370 2195005..2195346 + 342 WP_000976472.1 YebY family protein -
- 2195374..2195645 - 272 - - Antitoxin
- 2195504..2195607 + 104 - - Toxin
H7R14_RS10375 2195742..2196398 + 657 WP_001551231.1 protein-serine/threonine phosphatase -
H7R14_RS10380 2196399..2196590 - 192 WP_001296140.1 YebW family protein -
H7R14_RS10385 2196695..2196931 - 237 WP_001295499.1 DUF1480 family protein -
H7R14_RS10390 2197049..2198488 - 1440 WP_024186439.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T34263 NZ_AP022049:2195504-2195607 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT34263 NZ_AP022049:c2195645-2195374 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGCCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References