Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2183596..2183864 Replicon chromosome
Accession NZ_AP022044
Organism Escherichia coli strain WP4-S17-ESBL-03

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2183724..2183826 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2183596..2183864 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H7R12_RS10440 2180149..2180811 - 663 WP_000944256.1 exodeoxyribonuclease X -
H7R12_RS10445 2180835..2181491 - 657 WP_000011664.1 carbon-nitrogen hydrolase family protein -
H7R12_RS10450 2181593..2181823 - 231 WP_000916763.1 DNA polymerase III subunit theta -
H7R12_RS10455 2181962..2182336 + 375 WP_000168747.1 CopC domain-containing protein YobA -
H7R12_RS10460 2182340..2183212 + 873 WP_000879317.1 copper homeostasis membrane protein CopD -
H7R12_RS10465 2183225..2183566 + 342 WP_000976472.1 YebY family protein -
- 2183596..2183864 - 269 - - Antitoxin
- 2183724..2183826 + 103 - - Toxin
H7R12_RS10470 2183961..2184617 + 657 WP_000812745.1 protein-serine/threonine phosphatase -
H7R12_RS10475 2184618..2184809 - 192 WP_001296140.1 YebW family protein -
H7R12_RS10480 2184916..2185152 - 237 WP_001295499.1 DUF1480 family protein -
H7R12_RS10485 2185269..2186708 - 1440 WP_001296139.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T34236 NZ_AP022044:2183724-2183826 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT34236 NZ_AP022044:c2183864-2183596 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATATTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References