Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 3778286..3778854 Replicon chromosome
Accession NZ_AP022038
Organism Aeromonas veronii strain WP3-W19-ESBL-03

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag H7R62_RS17570 Protein ID WP_101617266.1
Coordinates 3778561..3778854 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag H7R62_RS17565 Protein ID WP_101617265.1
Coordinates 3778286..3778573 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H7R62_RS17530 3773429..3774325 + 897 WP_011191354.1 LysR family transcriptional regulator -
H7R62_RS17535 3774322..3774561 - 240 WP_018429611.1 DUF2274 domain-containing protein -
H7R62_RS17540 3774561..3775781 - 1221 WP_011191355.1 TrbI/VirB10 family protein -
H7R62_RS17545 3775778..3776827 - 1050 WP_011191356.1 P-type conjugative transfer protein TrbG -
H7R62_RS17550 3776824..3777141 - 318 Protein_3395 conjugal transfer protein TrbF -
H7R62_RS17555 3777234..3777431 - 198 WP_161508007.1 chromosome partitioning protein ParB -
H7R62_RS17560 3777452..3778081 - 630 WP_182935892.1 AAA family ATPase -
H7R62_RS17565 3778286..3778573 + 288 WP_101617265.1 CopG family ribbon-helix-helix protein Antitoxin
H7R62_RS17570 3778561..3778854 + 294 WP_101617266.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
H7R62_RS17575 3778980..3780116 - 1137 WP_182938062.1 sel1 repeat family protein -
H7R62_RS17580 3780147..3781415 - 1269 WP_011191342.1 IS4-like element ISApu1 family transposase -
H7R62_RS17585 3781733..3782104 - 372 WP_004099020.1 hypothetical protein -
H7R62_RS17590 3782261..3783535 + 1275 WP_011191341.1 IS4-like element ISApu2 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - katA 3708232..3784350 76118


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-94)

Antitoxin

Ribbon-helix-helix protein, CopG

(8-45)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10980.79 Da        Isoelectric Point: 10.6871

>T34227 WP_101617266.1 NZ_AP022038:3778561-3778854 [Aeromonas veronii]
MPPVIFAPAALRDLQRLREFLRPKSPQVAQRAATTIQLSLRQLAAQPSMGRPIEGLPEAFREWVIPFGDSGYLARYRIEP
DVIVVLAVRHQREVGYS

Download         Length: 294 bp

>T34227 NZ_AP022038:3778561-3778854 [Aeromonas veronii]
ATGCCACCAGTGATCTTTGCCCCTGCCGCCCTGCGAGACCTGCAACGCCTACGTGAATTCCTGCGCCCTAAAAGCCCGCA
GGTCGCACAGCGGGCCGCAACAACAATCCAGCTGTCCCTACGCCAGCTCGCAGCCCAACCCTCAATGGGCCGCCCCATAG
AAGGACTGCCAGAGGCGTTTCGTGAGTGGGTGATCCCCTTTGGTGACAGCGGCTATTTAGCCCGCTATCGCATTGAACCG
GATGTCATCGTGGTGCTCGCTGTCCGCCATCAACGCGAAGTTGGCTACTCATGA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 11047.15 Da        Isoelectric Point: 4.7091

>AT34227 WP_101617265.1 NZ_AP022038:3778286-3778573 [Aeromonas veronii]
MPTQSKPVSIKLDADTQERIKRLATSRERSAHWLMREAISQYVEREELRETFHRDTLEAWQEFQETGQYATAQDVDQWLA
SWGTDAEGAPPACHQ

Download         Length: 288 bp

>AT34227 NZ_AP022038:3778286-3778573 [Aeromonas veronii]
ATGCCCACACAATCCAAACCGGTCTCGATCAAACTCGACGCCGATACCCAGGAACGCATCAAACGCCTGGCAACCTCCCG
CGAACGCTCAGCCCATTGGCTCATGCGCGAAGCCATCAGCCAGTATGTCGAGCGCGAAGAACTGCGCGAGACCTTCCACC
GCGACACTCTGGAGGCCTGGCAGGAGTTCCAGGAGACCGGCCAGTATGCCACCGCTCAAGATGTGGATCAGTGGCTAGCC
TCTTGGGGCACTGATGCCGAAGGAGCGCCTCCTGCATGCCACCAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References