Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 710345..712059 Replicon chromosome
Accession NZ_AP022038
Organism Aeromonas veronii strain WP3-W19-ESBL-03

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag H7R62_RS03465 Protein ID WP_182938866.1
Coordinates 710345..710998 (+) Length 218 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID A0A8I0BGM7
Locus tag H7R62_RS03470 Protein ID WP_025201144.1
Coordinates 710995..712059 (+) Length 355 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H7R62_RS03445 705376..705564 + 189 WP_021138010.1 DUF3283 family protein -
H7R62_RS03450 705711..706157 + 447 WP_043852095.1 hypothetical protein -
H7R62_RS03455 706344..708791 + 2448 WP_113995997.1 type I restriction-modification system subunit M -
H7R62_RS03460 708791..710068 + 1278 WP_113995996.1 restriction endonuclease subunit S -
H7R62_RS03465 710345..710998 + 654 WP_182938866.1 DUF4433 domain-containing protein Toxin
H7R62_RS03470 710995..712059 + 1065 WP_025201144.1 macro domain-containing protein Antitoxin
H7R62_RS03475 712134..715264 + 3131 Protein_656 HsdR family type I site-specific deoxyribonuclease -
H7R62_RS03480 715264..715977 + 714 WP_005331303.1 M48 family metallopeptidase -
H7R62_RS03485 715996..716933 - 938 Protein_658 restriction endonuclease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 691268..720992 29724


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(17-216)

Antitoxin

Macro domain

(18-131)


Sequences

Toxin        


Download         Length: 218 a.a.        Molecular weight: 25484.13 Da        Isoelectric Point: 7.0177

>T34224 WP_182938866.1 NZ_AP022038:710345-710998 [Aeromonas veronii]
MAYDYSQSLNPQKALIFRIVHRDNLEWILTHGLWAGNGQQQNPHWVHIGLPELIAKRARHPVPLVPYGVLNDYVPFYFTP
FSPMLSNIHSGRGVPRRENDEILILVSSLHRMPELGLPFVFTDSHAYYQWANFYAELGDLERIDWPLLQRRDFKRDADDL
SKLERYQAEALIHQHCPIEALLGVVCYNEEIKNRVEQCMNRVGVARPVYVRDGWYFR

Download         Length: 654 bp

>T34224 NZ_AP022038:710345-710998 [Aeromonas veronii]
ATGGCCTATGACTATAGCCAGAGCCTGAATCCGCAGAAGGCGCTGATATTCCGGATCGTGCATCGGGATAACCTGGAATG
GATCCTGACCCATGGCCTGTGGGCGGGGAATGGTCAGCAGCAAAACCCGCACTGGGTGCATATCGGGTTGCCGGAGCTGA
TTGCCAAGCGCGCGCGCCATCCGGTGCCGCTGGTGCCTTACGGCGTGTTGAATGACTATGTGCCCTTCTACTTCACGCCG
TTTTCTCCCATGCTCAGCAATATTCACTCGGGGCGCGGTGTTCCCCGGCGTGAAAATGATGAAATCCTGATCCTGGTTTC
CAGCCTGCATCGCATGCCTGAATTGGGGCTACCGTTTGTGTTTACCGATAGCCATGCCTATTACCAGTGGGCCAATTTCT
ATGCCGAGCTTGGCGATCTGGAGCGGATTGACTGGCCACTGTTGCAGCGCCGTGATTTCAAGCGTGATGCGGACGATTTG
AGCAAGCTGGAGCGCTATCAGGCCGAGGCCTTGATCCATCAACATTGCCCCATCGAGGCATTGCTGGGTGTGGTGTGTTA
CAACGAAGAGATAAAGAACCGCGTGGAACAATGCATGAATCGGGTCGGGGTCGCGCGCCCCGTCTATGTCCGTGATGGGT
GGTATTTCAGATGA

Antitoxin


Download         Length: 355 a.a.        Molecular weight: 39563.71 Da        Isoelectric Point: 6.1433

>AT34224 WP_025201144.1 NZ_AP022038:710995-712059 [Aeromonas veronii]
MIRYTTGNLLDAPVEALVNTVNTVGVMGKGIALMFKERFPANMRAYAEACKQGDVVTGKMFITQTGELLGPRWIVNFPTK
QHWRNPAQMAWIQDGLQDLRAWLQAQQVSSIAIPPLGAGNGGLPWPEVKQAIETALGDLDIDILLYEPSSQYQNVAKRGG
VAELTPARALIAELVRRYWFLGMECSLLEIQKLAWFLARVIGLNPLGDPLQLQFKAHRYGPYANNLTHLLNAMDGSYLQS
DKRIPDSKPFDVIWFNEAKKQELAVYLNTEAKAFLPILEQTTALIDGFESPYGMELLATVDWLMVEEGCAPTLSALREGL
HRWPAGTPWGDRKARLFDDRSLQIALTRLQQGLV

Download         Length: 1065 bp

>AT34224 NZ_AP022038:710995-712059 [Aeromonas veronii]
ATGATTCGATATACAACAGGCAACCTGCTGGATGCTCCGGTGGAAGCACTGGTGAATACCGTCAACACAGTCGGTGTCAT
GGGCAAGGGGATCGCCTTGATGTTCAAGGAGCGGTTCCCGGCCAATATGCGTGCCTATGCCGAGGCGTGCAAGCAGGGTG
ACGTCGTCACCGGCAAGATGTTTATTACCCAGACGGGTGAGCTGCTAGGGCCGCGCTGGATCGTCAACTTTCCGACCAAA
CAGCACTGGCGCAATCCGGCACAGATGGCGTGGATCCAGGACGGTTTGCAGGATCTGCGGGCCTGGTTACAGGCGCAGCA
GGTCTCCTCGATTGCCATTCCACCACTGGGGGCTGGCAACGGTGGTCTGCCTTGGCCGGAGGTCAAACAGGCGATCGAAA
CGGCACTGGGCGATCTGGATATCGATATCCTGCTCTATGAGCCCAGTAGCCAATACCAAAATGTGGCCAAGCGCGGCGGG
GTGGCGGAGCTGACTCCGGCCCGGGCCCTGATTGCTGAACTGGTGCGTCGCTACTGGTTTTTAGGGATGGAGTGCAGCTT
GCTGGAGATCCAGAAACTGGCCTGGTTTCTGGCTCGGGTCATTGGCCTTAACCCGCTGGGGGATCCGCTGCAGTTGCAGT
TTAAGGCCCATCGTTATGGCCCTTATGCCAACAATCTGACCCATCTGCTCAATGCGATGGACGGCAGTTATCTGCAGTCC
GACAAGCGCATCCCGGATAGCAAGCCGTTTGATGTCATCTGGTTTAATGAGGCTAAAAAACAAGAGCTTGCCGTTTATCT
CAATACCGAGGCCAAAGCATTTTTACCGATACTGGAGCAGACGACCGCGTTAATCGATGGTTTTGAGTCGCCCTATGGCA
TGGAGTTATTGGCCACGGTGGACTGGCTGATGGTCGAAGAGGGCTGTGCGCCGACACTGAGCGCGCTGCGCGAGGGGTTG
CACCGCTGGCCAGCGGGAACCCCGTGGGGTGATCGCAAGGCGCGGCTGTTTGATGATCGCAGCCTGCAGATCGCCTTGAC
CCGTTTGCAGCAGGGATTGGTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References