Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1937253..1937524 Replicon chromosome
Accession NZ_AP022030
Organism Escherichia coli strain WP3-S18-ESBL-07

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1937383..1937486 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1937253..1937524 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H7R16_RS09280 1933808..1934470 - 663 WP_000944256.1 exodeoxyribonuclease X -
H7R16_RS09285 1934494..1935150 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
H7R16_RS09290 1935252..1935482 - 231 WP_000916763.1 DNA polymerase III subunit theta -
H7R16_RS09295 1935621..1935995 + 375 WP_000168747.1 CopC domain-containing protein YobA -
H7R16_RS09300 1935999..1936871 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
H7R16_RS09305 1936884..1937225 + 342 WP_000976476.1 YebY family protein -
- 1937253..1937524 - 272 - - Antitoxin
- 1937383..1937486 + 104 - - Toxin
H7R16_RS09310 1937621..1938277 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
H7R16_RS09315 1938278..1938469 - 192 WP_000457842.1 YebW family protein -
H7R16_RS09320 1938574..1938810 - 237 WP_001295499.1 DUF1480 family protein -
H7R16_RS09325 1938928..1940367 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T34145 NZ_AP022030:1937383-1937486 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT34145 NZ_AP022030:c1937524-1937253 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References