Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1970575..1970722 Replicon chromosome
Accession NZ_AP022014
Organism Klebsiella quasipneumoniae strain WP3-S18-ESBL-03

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1970616..1970718 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1970575..1970722 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H7R87_RS09525 1965710..1967770 + 2061 WP_182971857.1 oligopeptidase B -
H7R87_RS09530 1967774..1968433 - 660 WP_004203387.1 exodeoxyribonuclease X -
H7R87_RS09535 1968512..1968742 - 231 WP_002911406.1 DNA polymerase III subunit theta -
H7R87_RS09540 1968855..1969229 + 375 WP_004203386.1 CopC domain-containing protein YobA -
H7R87_RS09545 1969233..1970102 + 870 WP_004203385.1 copper homeostasis membrane protein CopD -
H7R87_RS09550 1970119..1970457 + 339 WP_002911404.1 YebY family protein -
- 1970575..1970722 - 148 - - Antitoxin
- 1970616..1970718 + 103 - - Toxin
H7R87_RS09555 1971106..1971249 - 144 WP_032425946.1 Ecr family regulatory small membrane protein -
H7R87_RS09560 1971353..1972321 - 969 WP_182971858.1 VirK/YbjX family protein -
H7R87_RS09565 1972478..1973131 + 654 WP_182971859.1 protein-serine/threonine phosphatase -
H7R87_RS09570 1973128..1973319 - 192 WP_002911395.1 YebW family protein -
H7R87_RS09575 1973417..1973656 - 240 WP_002911393.1 YebV family protein -
H7R87_RS09580 1973773..1975206 - 1434 WP_182971860.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T34121 NZ_AP022014:1970616-1970718 [Klebsiella quasipneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 148 bp

>AT34121 NZ_AP022014:c1970722-1970575 [Klebsiella quasipneumoniae]
AGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTG
GCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGTCTGCG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References