34068

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2184735..2185006 Replicon chromosome
Accession NZ_AP022003
Organism Escherichia coli strain WP3-W18-ESBL-08

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2184865..2184968 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2184735..2185006 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H7R22_RS10395 2181290..2181952 - 663 WP_000944256.1 exodeoxyribonuclease X -
H7R22_RS10400 2181976..2182632 - 657 WP_000011653.1 carbon-nitrogen hydrolase family protein -
H7R22_RS10405 2182734..2182964 - 231 WP_000916763.1 DNA polymerase III subunit theta -
H7R22_RS10410 2183103..2183477 + 375 WP_000168747.1 CopC domain-containing protein YobA -
H7R22_RS10415 2183481..2184353 + 873 WP_001551232.1 copper homeostasis membrane protein CopD -
H7R22_RS10420 2184366..2184707 + 342 WP_000976472.1 YebY family protein -
- 2184735..2185006 - 272 - - Antitoxin
- 2184865..2184968 + 104 - - Toxin
H7R22_RS10425 2185103..2185759 + 657 WP_001551231.1 protein-serine/threonine phosphatase -
H7R22_RS10430 2185760..2185951 - 192 WP_001296140.1 YebW family protein -
H7R22_RS10435 2186056..2186292 - 237 WP_001295499.1 DUF1480 family protein -
H7R22_RS10440 2186410..2187849 - 1440 WP_024186439.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2177425..2200846 23421


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T34068 NZ_AP022003:2184865-2184968 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT34068 NZ_AP022003:c2185006-2184735 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGCCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References