Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2162291..2162559 Replicon chromosome
Accession NZ_AP021998
Organism Escherichia coli strain WP3-W18-ESBL-07

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2162419..2162521 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2162291..2162559 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H7Q99_RS10240 2158844..2159506 - 663 WP_000944256.1 exodeoxyribonuclease X -
H7Q99_RS10245 2159530..2160186 - 657 WP_000011664.1 carbon-nitrogen hydrolase family protein -
H7Q99_RS10250 2160288..2160518 - 231 WP_000916763.1 DNA polymerase III subunit theta -
H7Q99_RS10255 2160657..2161031 + 375 WP_000168747.1 CopC domain-containing protein YobA -
H7Q99_RS10260 2161035..2161907 + 873 WP_000879317.1 copper homeostasis membrane protein CopD -
H7Q99_RS10265 2161920..2162261 + 342 WP_000976472.1 YebY family protein -
- 2162291..2162559 - 269 - - Antitoxin
- 2162419..2162521 + 103 - - Toxin
H7Q99_RS10270 2162656..2163312 + 657 WP_000812745.1 protein-serine/threonine phosphatase -
H7Q99_RS10275 2163313..2163504 - 192 WP_001296140.1 YebW family protein -
H7Q99_RS10280 2163609..2163845 - 237 WP_001295499.1 DUF1480 family protein -
H7Q99_RS10285 2163962..2165401 - 1440 WP_001296139.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T34034 NZ_AP021998:2162419-2162521 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT34034 NZ_AP021998:c2162559-2162291 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATATTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References