Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2086389..2086531 | Replicon | chromosome |
| Accession | NZ_AP021972 | ||
| Organism | Klebsiella sp. WP3-W18-ESBL-02 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2086425..2086527 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2086389..2086531 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| H7R56_RS09780 | 2082867..2083526 | - | 660 | WP_106927750.1 | exodeoxyribonuclease X | - |
| H7R56_RS09785 | 2083549..2084217 | - | 669 | WP_106927748.1 | carbon-nitrogen hydrolase family protein | - |
| H7R56_RS09790 | 2084305..2084535 | - | 231 | WP_106927746.1 | DNA polymerase III subunit theta | - |
| H7R56_RS09795 | 2084673..2085047 | + | 375 | WP_106927913.1 | CopC domain-containing protein YobA | - |
| H7R56_RS09800 | 2085050..2085922 | + | 873 | WP_106927744.1 | copper homeostasis membrane protein CopD | - |
| H7R56_RS09805 | 2085938..2086273 | + | 336 | WP_106927742.1 | YebY family protein | - |
| - | 2086389..2086531 | - | 143 | - | - | Antitoxin |
| - | 2086425..2086527 | + | 103 | - | - | Toxin |
| H7R56_RS09810 | 2086605..2087690 | - | 1086 | WP_182928594.1 | tyrosine-type recombinase/integrase | - |
| H7R56_RS09815 | 2087659..2087931 | - | 273 | WP_182928595.1 | excisionase | - |
| H7R56_RS09820 | 2087993..2088235 | - | 243 | WP_182928596.1 | DUF4060 family protein | - |
| H7R56_RS09825 | 2088232..2088654 | - | 423 | WP_182928597.1 | PerC family transcriptional regulator | - |
| H7R56_RS09830 | 2088690..2089730 | - | 1041 | WP_182928598.1 | recombinase RecT | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 2065402..2164945 | 99543 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T33981 NZ_AP021972:2086425-2086527 [Klebsiella sp. WP3-W18-ESBL-02]
GCATGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCATGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 143 bp
>AT33981 NZ_AP021972:c2086531-2086389 [Klebsiella sp. WP3-W18-ESBL-02]
AGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTG
GCATTAATGCAGGCTAAGTCGCCATGCTTTATAAGAATAGATGACCGTGACAGGTTTTCCAGT
AGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTG
GCATTAATGCAGGCTAAGTCGCCATGCTTTATAAGAATAGATGACCGTGACAGGTTTTCCAGT
