Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2195759..2196027 Replicon chromosome
Accession NZ_AP021963
Organism Escherichia coli strain WP3-W18-CRE-03

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2195887..2195989 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2195759..2196027 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H7R02_RS10375 2192312..2192974 - 663 WP_000944258.1 exodeoxyribonuclease X -
H7R02_RS10380 2192998..2193654 - 657 WP_000011664.1 carbon-nitrogen hydrolase family protein -
H7R02_RS10385 2193756..2193986 - 231 WP_000916763.1 DNA polymerase III subunit theta -
H7R02_RS10390 2194125..2194499 + 375 WP_000168747.1 CopC domain-containing protein YobA -
H7R02_RS10395 2194503..2195375 + 873 WP_000879311.1 copper homeostasis membrane protein CopD -
H7R02_RS10400 2195388..2195729 + 342 WP_000984819.1 YebY family protein -
- 2195759..2196027 - 269 - - Antitoxin
- 2195887..2195989 + 103 - - Toxin
H7R02_RS10405 2196124..2196780 + 657 WP_000812744.1 protein-serine/threonine phosphatase -
H7R02_RS10410 2196781..2196972 - 192 WP_024186842.1 YebW family protein -
H7R02_RS10415 2197077..2197313 - 237 WP_001295499.1 DUF1480 family protein -
H7R02_RS10420 2197432..2198871 - 1440 WP_024186841.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T33948 NZ_AP021963:2195887-2195989 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT33948 NZ_AP021963:c2196027-2195759 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References