Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2192509..2192780 Replicon chromosome
Accession NZ_AP021946
Organism Escherichia coli strain WP2-S18-ESBL-08

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2192639..2192742 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2192509..2192780 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H7R07_RS10595 2189064..2189726 - 663 WP_182913120.1 exodeoxyribonuclease X -
H7R07_RS10600 2189750..2190406 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
H7R07_RS10605 2190508..2190738 - 231 WP_000916763.1 DNA polymerase III subunit theta -
H7R07_RS10610 2190877..2191251 + 375 WP_000168747.1 CopC domain-containing protein YobA -
H7R07_RS10615 2191255..2192127 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
H7R07_RS10620 2192140..2192481 + 342 WP_000976476.1 YebY family protein -
- 2192509..2192780 - 272 - - Antitoxin
- 2192639..2192742 + 104 - - Toxin
H7R07_RS10625 2192877..2193533 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
H7R07_RS10630 2193534..2193725 - 192 WP_000457842.1 YebW family protein -
H7R07_RS10635 2193830..2194066 - 237 WP_001295499.1 DUF1480 family protein -
H7R07_RS10640 2194184..2195623 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T33885 NZ_AP021946:2192639-2192742 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT33885 NZ_AP021946:c2192780-2192509 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References