33753

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 1055874..1057588 Replicon chromosome
Accession NZ_AP021927
Organism Aeromonas caviae strain WP2-W18-ESBL-01

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag H7R60_RS05190 Protein ID WP_182935897.1
Coordinates 1055874..1056527 (+) Length 218 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag H7R60_RS05195 Protein ID WP_182935898.1
Coordinates 1056524..1057588 (+) Length 355 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H7R60_RS05175 1051151..1051597 + 447 WP_043852095.1 hypothetical protein -
H7R60_RS05180 1051783..1054230 + 2448 WP_182935895.1 type I restriction-modification system subunit M -
H7R60_RS05185 1054230..1055609 + 1380 WP_182935896.1 restriction endonuclease subunit S -
H7R60_RS05190 1055874..1056527 + 654 WP_182935897.1 DUF4433 domain-containing protein Toxin
H7R60_RS05195 1056524..1057588 + 1065 WP_182935898.1 macro domain-containing protein Antitoxin
H7R60_RS05200 1057663..1060794 + 3132 WP_182935899.1 HsdR family type I site-specific deoxyribonuclease -
H7R60_RS05205 1060794..1061507 + 714 WP_005331303.1 M48 family metallopeptidase -
H7R60_RS05210 1061526..1061720 - 195 Protein_978 restriction endonuclease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1009995..1069741 59746


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(17-216)

Antitoxin

Macro domain

(18-131)


Sequences

Toxin        


Download         Length: 218 a.a.        Molecular weight: 25415.07 Da        Isoelectric Point: 7.0177

>T33753 WP_182935897.1 NZ_AP021927:1055874-1056527 [Aeromonas caviae]
MAYDYSQSLNPEKALIFRIVHRDNLEWILTHGLWAGNGQQQNPHWVHIGLPELIAKRARHPVPLVPYGVLNDYVPFYFTP
FSPMLSNIHSGRGVPRRENDEILILVSSLHRMAELGLPFVFTDSHAYYQWANFYVDLGDLGRIDWPLLQRRDFKRDAEDL
SKLERYQAEALIHQHCPIEALLGVVCYNEEIKNRVEQCMNRVGVARPVYVRDGWYFR

Download         Length: 654 bp

>T33753 NZ_AP021927:1055874-1056527 [Aeromonas caviae]
ATGGCCTATGACTATAGCCAGAGCCTGAATCCGGAGAAGGCGCTGATATTCCGGATCGTGCATCGGGATAACCTGGAATG
GATCCTGACCCATGGCCTGTGGGCGGGGAATGGTCAGCAGCAAAACCCGCACTGGGTGCATATCGGGTTGCCGGAGCTGA
TTGCCAAGCGCGCGCGTCATCCGGTGCCGCTGGTGCCTTACGGCGTGTTGAATGACTATGTGCCCTTCTATTTCACGCCG
TTTTCTCCCATGCTCAGCAATATTCACTCGGGGCGCGGTGTTCCCCGGCGTGAAAATGATGAAATCCTGATCCTGGTTTC
CAGCCTGCATCGCATGGCTGAATTGGGGCTACCGTTTGTGTTTACCGATAGCCATGCCTATTACCAGTGGGCCAATTTCT
ATGTCGATCTTGGCGATCTGGGGCGGATTGACTGGCCACTGTTGCAGCGCCGTGACTTCAAGCGTGATGCGGAAGATTTG
AGCAAGCTGGAACGCTATCAGGCCGAGGCCTTGATCCATCAACATTGCCCCATCGAGGCGTTGCTGGGCGTGGTGTGTTA
CAACGAAGAGATAAAGAACCGCGTGGAACAGTGCATGAATCGGGTCGGGGTCGCGCGCCCCGTCTATGTCCGTGATGGGT
GGTATTTCAGATGA

Antitoxin


Download         Length: 355 a.a.        Molecular weight: 39686.90 Da        Isoelectric Point: 7.2911

>AT33753 WP_182935898.1 NZ_AP021927:1056524-1057588 [Aeromonas caviae]
MIRYTTGNLLDAPVEALVNTVNTVGVMGKGIALMFKERFPANMRAYAEACKQGDVVTGKMFITQTGELLGPRWIVNFPTK
QHWRNPAQMAWIQEGLQNLRAWLQAQQVSSIAIPPLGAGNGGLPWLEVKQAIETALGDLDIDILLYEPSRQYQNVAKRGG
VAELTPARALIAELVRRYWFLGMECSLLEIQKLAWFLARVIGRNPLGDPLQLQFKAHRYGPYANNLTHLLNAMDGSYLQS
DKRIPDSKPFDVIWFNEAKKQELAVYLQTEAKAFLPILEQTTALIDGFESPYGMELLATVDWLIAEEGCAPTLSALREGL
HRWPAGTPWGERKARLFDDRSLQIALTRLQQGLV

Download         Length: 1065 bp

>AT33753 NZ_AP021927:1056524-1057588 [Aeromonas caviae]
ATGATTCGATATACAACAGGCAATCTGCTGGATGCTCCGGTGGAAGCGCTGGTGAATACCGTCAACACCGTCGGTGTCAT
GGGCAAGGGGATCGCCTTGATGTTCAAGGAGCGGTTCCCGGCCAATATGCGTGCCTATGCCGAGGCGTGCAAGCAGGGTG
ACGTCGTCACCGGCAAGATGTTTATTACCCAGACGGGTGAGCTGCTGGGGCCACGCTGGATCGTGAATTTTCCGACCAAA
CAGCACTGGCGCAATCCGGCACAGATGGCGTGGATCCAGGAGGGTTTGCAGAATCTGCGGGCCTGGTTACAGGCGCAGCA
GGTCTCCTCGATTGCCATTCCACCACTGGGGGCTGGCAACGGTGGTCTGCCTTGGCTGGAGGTCAAACAGGCGATTGAAA
CGGCACTGGGCGATCTGGATATCGATATCCTGCTCTATGAGCCCAGTCGCCAATACCAAAATGTGGCCAAGCGTGGCGGG
GTGGCGGAGCTGACTCCGGCTCGGGCCTTGATTGCTGAACTGGTACGTCGCTACTGGTTTTTAGGGATGGAGTGCAGCTT
GCTGGAAATCCAGAAGCTGGCCTGGTTTCTGGCTCGGGTCATTGGCCGCAACCCGCTGGGGGATCCGCTGCAGTTGCAGT
TTAAGGCCCATCGTTATGGCCCTTATGCCAACAATCTGACCCATCTGCTCAATGCGATGGACGGCAGTTATCTACAGTCC
GACAAGCGCATCCCGGATAGCAAGCCGTTTGATGTCATCTGGTTTAATGAGGCTAAAAAACAAGAGCTTGCCGTTTATCT
CCAGACCGAGGCCAAAGCATTTTTACCGATACTGGAGCAGACGACCGCGTTAATCGATGGTTTTGAGTCGCCCTATGGCA
TGGAGTTATTGGCCACGGTCGATTGGTTGATCGCCGAAGAGGGCTGTGCGCCGACACTGAGCGCGCTGCGCGAGGGGTTG
CACCGCTGGCCAGCGGGAACCCCGTGGGGTGAGCGCAAGGCGCGGCTGTTTGATGATCGCAGTCTGCAGATCGCCTTGAC
CCGTTTGCAGCAGGGATTGGTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References