Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 717695..719163 Replicon chromosome
Accession NZ_AP021908
Organism Stenotrophomonas maltophilia strain WP1-W18-CRE-01

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag H7X90_RS03245 Protein ID WP_157803285.1
Coordinates 717695..718564 (-) Length 290 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag H7X90_RS03250 Protein ID WP_032966430.1
Coordinates 718561..719163 (-) Length 201 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H7X90_RS03225 713873..714451 - 579 WP_012479148.1 metal-dependent hydrolase -
H7X90_RS03230 714562..714930 - 369 WP_012479149.1 YraN family protein -
H7X90_RS03235 714920..716641 - 1722 WP_183153771.1 penicillin-binding protein activator -
H7X90_RS03240 716723..717541 + 819 WP_005408070.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
H7X90_RS03245 717695..718564 - 870 WP_157803285.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
H7X90_RS03250 718561..719163 - 603 WP_032966430.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
H7X90_RS03260 719907..720377 - 471 WP_049397418.1 DM13 domain-containing protein -
H7X90_RS03265 720479..721255 - 777 WP_065183610.1 NRDE family protein -
H7X90_RS03270 721579..722025 + 447 WP_004143635.1 division/cell wall cluster transcriptional repressor MraZ -
H7X90_RS03275 722040..723008 + 969 WP_012479154.1 16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH -
H7X90_RS03280 723005..723268 + 264 WP_005412242.1 cell division protein FtsL -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 694602..719163 24561


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(40-268)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(12-53)


Sequences

Toxin        


Download         Length: 290 a.a.        Molecular weight: 32579.23 Da        Isoelectric Point: 6.3012

>T33696 WP_157803285.1 NZ_AP021908:c718564-717695 [Stenotrophomonas maltophilia]
VTHSPPLPQRVASIRQRLLDLARSRGEDFQFVLDRFAVERLLYRLSASRYRDQFLLKGAMLFAVWFDAPHRPTRDADFLR
FGSADPDHLLHIARSLCAIPDDDGLCFDPGSIAIEATREEAEYEGLRIRLTAHLGRSRCHVQWDVGFGDAVTPPPPEIAY
PVMLDGFPLPCLHVYPRETVFAEKLEAIAALGIANSRMKDFFDLLALVREDAMDRPHLVAAIGATFDRRRTPAPPPLPYG
LTQSFAADTQKQTQWRAFLRRNRLIAPDLSSVIAEIADYLDTLDTTVQS

Download         Length: 870 bp

>T33696 NZ_AP021908:c718564-717695 [Stenotrophomonas maltophilia]
GTGACCCACTCTCCACCACTCCCCCAGCGCGTTGCTTCCATCCGGCAACGGCTGCTCGATCTCGCTCGCAGCCGAGGCGA
GGACTTTCAGTTCGTGCTGGACCGGTTCGCCGTTGAGCGCCTGCTCTACCGACTCTCCGCTTCCCGATACCGCGACCAGT
TCCTGCTGAAGGGCGCCATGTTGTTTGCAGTGTGGTTCGACGCCCCCCACCGTCCCACGCGGGATGCCGATTTTCTGCGA
TTCGGCTCTGCAGATCCCGACCATCTGCTGCACATCGCACGGTCGCTCTGTGCAATACCGGACGACGACGGCCTATGCTT
CGACCCGGGCAGCATCGCCATCGAGGCCACCCGCGAAGAAGCGGAGTATGAGGGGTTGCGAATCCGCCTGACCGCACATC
TTGGCCGCTCGCGCTGCCACGTACAGTGGGACGTGGGGTTTGGCGATGCGGTGACTCCCCCACCGCCGGAAATCGCCTAC
CCGGTGATGCTGGATGGCTTTCCTCTCCCCTGCCTGCACGTCTATCCGCGCGAGACCGTGTTTGCCGAAAAGCTGGAGGC
CATTGCGGCACTGGGCATCGCAAACAGCAGGATGAAGGACTTCTTCGACTTGCTGGCACTGGTCCGCGAAGACGCCATGG
ATCGTCCACACCTTGTTGCGGCCATTGGCGCGACGTTTGATCGGCGAAGGACCCCGGCGCCGCCCCCCTTGCCCTACGGA
CTGACTCAGTCGTTCGCCGCAGATACCCAGAAGCAGACCCAGTGGCGCGCCTTCCTGCGCAGGAATCGCCTGATCGCGCC
GGATCTCTCTTCGGTGATTGCCGAGATTGCCGACTATCTGGACACCCTCGACACAACCGTACAGTCCTGA

Antitoxin


Download         Length: 201 a.a.        Molecular weight: 22331.07 Da        Isoelectric Point: 11.2557

>AT33696 WP_032966430.1 NZ_AP021908:c719163-718561 [Stenotrophomonas maltophilia]
MGNAEANARKLLRRAGTLRARELVTAGIARAQLTRLVEAGALIRLSRGVYALAERNSDDTDDGLRIIAERLPHPRLCLLS
ALRLHGLTTQAPFERWVSIGNSDRVPRIDWPPLRVVRMSAKTLNAGLEERRVGKRLIYVSNVAKTVVDCFKFRNLVGLDV
AIEALRDALHSRATTPDALMEYARICRVARLMRPYLDALA

Download         Length: 603 bp

>AT33696 NZ_AP021908:c719163-718561 [Stenotrophomonas maltophilia]
ATGGGAAACGCCGAGGCCAACGCACGAAAGCTGTTGCGACGCGCAGGCACCCTGCGCGCCCGCGAGCTGGTGACCGCCGG
GATCGCCCGCGCCCAGCTGACCCGACTGGTCGAGGCCGGTGCGCTGATCCGGCTGTCTCGTGGCGTCTACGCGTTGGCGG
AAAGAAACAGTGACGACACCGATGATGGACTGCGGATCATTGCCGAACGCCTGCCGCACCCCCGTCTGTGCCTGTTGAGT
GCCCTGCGCCTGCATGGCCTGACCACCCAGGCGCCATTCGAACGCTGGGTCTCCATCGGCAACAGCGACCGCGTTCCGCG
GATCGATTGGCCGCCCCTCCGAGTGGTCCGCATGTCGGCAAAGACCCTCAACGCGGGGCTGGAAGAGCGTCGCGTAGGCA
AACGTCTCATATACGTCAGCAATGTAGCCAAAACCGTCGTCGATTGCTTCAAGTTCCGCAATCTCGTAGGACTTGATGTC
GCAATTGAAGCCCTGCGTGACGCGCTTCACAGCCGTGCGACCACGCCGGATGCGCTGATGGAGTATGCGCGGATCTGCCG
CGTTGCCAGACTGATGAGACCGTACCTCGATGCCCTGGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References