33693

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Xre(antitoxin)
Location 4921271..4922429 Replicon chromosome
Accession NZ_AP021905
Organism Pseudomonas sp. Pc102

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag PHLH3_RS22410 Protein ID WP_213625837.1
Coordinates 4921271..4922023 (-) Length 251 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag PHLH3_RS22415 Protein ID WP_111264584.1
Coordinates 4922058..4922429 (-) Length 124 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PHLH3_RS22390 (PHLH8_44520) 4916982..4917866 + 885 WP_213625834.1 metal-dependent hydrolase -
PHLH3_RS22395 (PHLH8_44530) 4917936..4919300 - 1365 WP_244863094.1 DNA recombination protein RmuC -
PHLH3_RS22400 (PHLH8_44540) 4919464..4919871 - 408 WP_111264581.1 SEL1-like repeat protein -
PHLH3_RS22405 (PHLH8_44550) 4920219..4921274 - 1056 WP_213625836.1 AraC family transcriptional regulator -
PHLH3_RS22410 (PHLH8_44560) 4921271..4922023 - 753 WP_213625837.1 RES family NAD+ phosphorylase Toxin
PHLH3_RS22415 (PHLH8_44570) 4922058..4922429 - 372 WP_111264584.1 DUF2384 domain-containing protein Antitoxin
PHLH3_RS22420 (PHLH8_44580) 4922553..4923035 + 483 WP_213625838.1 transcription elongation factor GreAB -
PHLH3_RS22425 (PHLH8_44590) 4923087..4923488 + 402 WP_213625839.1 hypothetical protein -
PHLH3_RS30520 4923682..4923867 + 186 WP_244862930.1 hypothetical protein -
PHLH3_RS22430 (PHLH8_44600) 4923891..4924340 - 450 WP_213625840.1 S24 family peptidase -
PHLH3_RS22435 (PHLH8_44610) 4924442..4926040 - 1599 WP_213625841.1 M28 family metallopeptidase -
PHLH3_RS22440 (PHLH8_44620) 4926548..4927099 + 552 WP_213625842.1 GNAT family N-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(58-206)

Antitoxin

Antitoxin Xre/MbcA/ParS-like, toxin-binding domain

(72-121)


Sequences

Toxin        


Download         Length: 251 a.a.        Molecular weight: 28167.20 Da        Isoelectric Point: 7.1064

>T33693 WP_213625837.1 NZ_AP021905:c4922023-4921271 [Pseudomonas sp. Pc102]
MDIWTTCQGPQHIGPLRGRLVRLVESQEQVATLQLVDNLAEQALLEELIETSKPPLPRSAEPLHYLLKTPFRYPPLRWGS
RFGTVHEPSLFYAASRLETAMAEGAFYRFVLWSGMAVPPPSGRILSEHSSFEARFQVERGVQLQLPPFDRHAQALADPVD
YRASQALGAAMRAAGVEAFEYRSARCPLQGTNIALFTPEAFTERRPRNLTPWLCETTAEYVAFKHAQAPDTPRLFRMTQF
LIDGHLPQPA

Download         Length: 753 bp

>T33693 NZ_AP021905:c4922023-4921271 [Pseudomonas sp. Pc102]
ATGGATATCTGGACGACCTGCCAGGGCCCGCAACACATCGGGCCCCTGCGTGGCCGCCTGGTGCGGCTGGTGGAGAGCCA
GGAGCAGGTGGCGACCCTGCAGCTGGTGGACAACCTCGCCGAACAGGCGTTGCTGGAGGAACTCATCGAGACCAGCAAGC
CGCCGTTGCCCAGGAGCGCCGAGCCGCTGCACTACCTGCTCAAGACCCCGTTCCGCTACCCGCCGCTGCGCTGGGGGTCG
CGCTTCGGCACCGTCCACGAGCCGAGCCTGTTCTACGCCGCCTCGCGCCTGGAGACCGCCATGGCCGAGGGGGCGTTCTA
CCGCTTCGTCCTGTGGAGCGGCATGGCCGTGCCGCCCCCCAGCGGGCGCATCCTGTCCGAGCATTCCTCCTTCGAGGCGC
GTTTCCAGGTGGAGCGTGGCGTGCAGCTGCAATTGCCGCCGTTCGATCGTCACGCTCAGGCACTGGCCGACCCGGTTGAC
TACCGCGCCAGCCAGGCGCTCGGCGCGGCCATGCGTGCCGCGGGCGTGGAGGCCTTCGAGTACCGCTCCGCGCGCTGCCC
GCTGCAGGGCACCAACATCGCCCTGTTCACCCCCGAGGCCTTCACCGAGCGGCGACCACGCAACCTCACGCCCTGGCTCT
GCGAGACCACCGCCGAGTACGTCGCCTTCAAGCATGCCCAGGCGCCGGATACACCGCGCCTGTTCCGCATGACGCAGTTC
CTGATCGACGGCCACCTGCCACAGCCGGCATGA

Antitoxin


Download         Length: 124 a.a.        Molecular weight: 13570.78 Da        Isoelectric Point: 10.2920

>AT33693 WP_111264584.1 NZ_AP021905:c4922429-4922058 [Pseudomonas sp. Pc102]
MSALSRPTLDPDAVLAKALLNTREQLGLTQQQLADIVGVHRTAITRWADSGGIRPQSKTGELALLLIRAYRALFALFGGN
LDDMRHFLRTENRHLGAVPLELMGQVQGLVRVVEYLDAIRGKI

Download         Length: 372 bp

>AT33693 NZ_AP021905:c4922429-4922058 [Pseudomonas sp. Pc102]
ATGAGCGCCCTCAGCCGTCCCACTCTCGATCCCGATGCCGTCCTGGCCAAGGCCCTGCTCAATACCCGCGAGCAACTCGG
GCTGACCCAGCAGCAACTGGCCGACATCGTCGGTGTGCACCGCACCGCCATCACCCGCTGGGCGGACAGCGGCGGCATCC
GTCCGCAGAGCAAGACCGGCGAGCTCGCGCTGCTGCTGATTCGCGCCTACCGCGCATTGTTCGCCCTGTTCGGCGGCAAC
CTCGACGACATGCGCCACTTCCTGCGCACCGAGAACCGCCACCTGGGCGCCGTTCCCCTCGAACTGATGGGCCAGGTGCA
GGGTCTGGTGAGGGTGGTGGAGTACCTGGACGCCATACGCGGCAAGATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References