Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Acetyltransf_4(toxin)
Location 4908432..4909840 Replicon chromosome
Accession NZ_AP021905
Organism Pseudomonas sp. Pc102

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag PHLH3_RS22365 Protein ID WP_213625829.1
Coordinates 4909271..4909840 (-) Length 190 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag PHLH3_RS22360 Protein ID WP_213625828.1
Coordinates 4908432..4909274 (-) Length 281 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PHLH3_RS22335 (PHLH8_44410) 4903852..4904799 + 948 WP_213625824.1 bile acid:sodium symporter family protein -
PHLH3_RS22340 (PHLH8_44420) 4904947..4905261 + 315 WP_173171966.1 quaternary ammonium compound efflux SMR transporter SugE -
PHLH3_RS22345 (PHLH8_44430) 4905325..4907199 - 1875 WP_213625825.1 MFS transporter -
PHLH3_RS22350 (PHLH8_44440) 4907352..4907681 - 330 WP_213625826.1 AzlD domain-containing protein -
PHLH3_RS22355 (PHLH8_44450) 4907681..4908394 - 714 WP_213625827.1 AzlC family ABC transporter permease -
PHLH3_RS22360 (PHLH8_44460) 4908432..4909274 - 843 WP_213625828.1 AraC family transcriptional regulator Antitoxin
PHLH3_RS22365 (PHLH8_44470) 4909271..4909840 - 570 WP_213625829.1 GNAT family protein Toxin
PHLH3_RS22370 (PHLH8_44480) 4910092..4913568 + 3477 WP_213625830.1 NahK/ErcS family hybrid sensor histidine kinase/response regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(14-146)

Antitoxin

AraC-type arabinose-binding/dimerisation domain

(17-149)


Sequences

Toxin        


Download         Length: 190 a.a.        Molecular weight: 21321.31 Da        Isoelectric Point: 7.4032

>T33692 WP_213625829.1 NZ_AP021905:c4909840-4909271 [Pseudomonas sp. Pc102]
MFNPQPVILQRGALRLEPLGEADITELSALAEANRDELVYMSGPLRPDWYRQGLAEQREGRAVVFAIRLGDRLVGTSRFA
DFMPALPAVEIGWTWLARSEHASGLNASIKYLMLRHAFEEWQVVRVQLKTAGSNLRSQKAIEKLGAQREGVLRNHRRLAD
GRLDDSVLYSITDHEWPAVKQALEASFSQ

Download         Length: 570 bp

>T33692 NZ_AP021905:c4909840-4909271 [Pseudomonas sp. Pc102]
ATGTTCAATCCGCAACCGGTCATCCTGCAGCGCGGCGCCTTGCGCCTCGAGCCGCTGGGGGAGGCCGACATCACCGAACT
TTCGGCGCTGGCCGAGGCCAATCGCGATGAGCTGGTCTACATGAGCGGCCCGCTGCGCCCGGACTGGTACCGCCAGGGCC
TGGCCGAGCAGCGTGAAGGCCGGGCCGTGGTGTTCGCCATCCGCCTGGGCGATCGCCTGGTGGGTACCAGCCGCTTCGCC
GATTTCATGCCCGCGCTGCCGGCCGTGGAGATCGGCTGGACCTGGCTGGCCCGCAGCGAGCACGCCAGCGGCCTCAATGC
CTCGATCAAGTACCTGATGCTGCGCCATGCCTTCGAGGAGTGGCAGGTGGTGCGCGTGCAACTGAAGACCGCCGGCAGCA
ACCTGCGCTCGCAGAAGGCCATCGAGAAACTCGGTGCCCAGCGCGAAGGCGTCCTGCGCAACCATCGCCGCCTGGCGGAC
GGGCGCCTCGACGACAGCGTGCTCTACAGCATCACCGACCATGAGTGGCCGGCCGTGAAGCAGGCCCTGGAAGCCTCTTT
CAGCCAATGA

Antitoxin


Download         Length: 281 a.a.        Molecular weight: 31230.60 Da        Isoelectric Point: 9.3725

>AT33692 WP_213625828.1 NZ_AP021905:c4909274-4908432 [Pseudomonas sp. Pc102]
MSAGGELTRFWQASALGGVELLHARYIEQRFSPHVHEGYVFTVLESGAQRFRHRGSDHLAAVGSMVLINPDELHTGSKAH
EEGWRYRGFYPDLHRVTEVLGELEIATGGLPTFADSVLHDPEVTRRFLDLHRLLERNASALEQQVAWREAILLLFSRHAR
IGAPRPAGQEPHAVALAREVLAARLASPPSLEELAALVGLSPFHFARVFRRATGLPPHAWLKQRRLEQARALLREGYAPL
PVAMQLGFADQSHLTRQFKQAYGVGPGEYRSACARSFKTC

Download         Length: 843 bp

>AT33692 NZ_AP021905:c4909274-4908432 [Pseudomonas sp. Pc102]
ATGAGCGCGGGTGGCGAGCTGACGCGCTTCTGGCAGGCCAGCGCGCTGGGCGGGGTCGAACTCCTGCACGCGCGCTACAT
CGAGCAGCGTTTCTCGCCCCATGTGCACGAGGGCTACGTCTTCACCGTCCTCGAATCCGGCGCCCAGCGCTTCCGCCACC
GCGGTAGCGACCACCTGGCTGCCGTCGGCAGCATGGTGCTGATCAACCCGGACGAGCTGCATACGGGCTCCAAGGCCCAC
GAGGAAGGGTGGCGCTACCGCGGCTTCTACCCCGACCTGCACCGGGTGACCGAGGTGCTGGGCGAACTGGAGATCGCCAC
CGGCGGCCTGCCCACCTTCGCCGACAGCGTGCTGCACGATCCCGAGGTGACCCGCCGCTTCCTCGACCTGCACCGCCTGC
TGGAGCGCAACGCCTCCGCCCTCGAGCAGCAGGTGGCCTGGCGCGAGGCGATCTTGCTGCTGTTCAGCCGCCACGCGCGC
ATTGGTGCGCCCCGGCCGGCAGGGCAGGAGCCCCATGCCGTGGCGCTGGCCCGCGAAGTGCTGGCGGCGCGCCTGGCCTC
GCCGCCATCCCTGGAGGAACTGGCCGCCCTGGTTGGGCTGTCGCCGTTCCATTTCGCCCGGGTGTTCCGCCGGGCCACCG
GGTTGCCGCCCCACGCCTGGCTGAAACAGCGTCGCCTGGAGCAGGCTCGGGCGCTGCTGCGCGAAGGCTACGCGCCGCTG
CCGGTAGCGATGCAACTGGGCTTCGCCGACCAGAGCCACCTGACCCGCCAGTTCAAGCAGGCTTACGGGGTCGGTCCGGG
CGAGTACCGCAGCGCCTGCGCAAGATCGTTCAAGACCTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References