Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 2615054..2616307 Replicon chromosome
Accession NZ_AP021905
Organism Pseudomonas sp. Pc102

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PHLH3_RS12175 Protein ID WP_213629469.1
Coordinates 2615723..2616307 (+) Length 195 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PHLH3_RS12170 Protein ID WP_213629468.1
Coordinates 2615054..2615611 (+) Length 186 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PHLH3_RS12150 (PHLH8_23980) 2610623..2611234 + 612 WP_213629465.1 LysE family translocator -
PHLH3_RS12155 (PHLH8_23990) 2611237..2613321 - 2085 WP_244863023.1 PAS domain S-box protein -
PHLH3_RS12160 (PHLH8_24000) 2613507..2614256 + 750 WP_213629466.1 NAD-dependent deacylase -
PHLH3_RS12165 (PHLH8_24010) 2614283..2614798 - 516 WP_213629467.1 thioredoxin family protein -
PHLH3_RS12170 (PHLH8_24020) 2615054..2615611 + 558 WP_213629468.1 helix-turn-helix transcriptional regulator Antitoxin
PHLH3_RS12175 (PHLH8_24030) 2615723..2616307 + 585 WP_213629469.1 HD domain-containing protein Toxin
PHLH3_RS12180 (PHLH8_24040) 2616518..2616901 + 384 WP_213629470.1 cytochrome c -
PHLH3_RS12185 2616921..2617061 - 141 WP_173174516.1 DUF2256 domain-containing protein -
PHLH3_RS12190 (PHLH8_24050) 2617058..2618602 - 1545 WP_213629471.1 cryptochrome/photolyase family protein -
PHLH3_RS12195 (PHLH8_24060) 2618596..2618901 - 306 WP_173174511.1 DUF6482 family protein -
PHLH3_RS12200 (PHLH8_24070) 2618932..2619468 - 537 WP_213629472.1 DUF3833 domain-containing protein -
PHLH3_RS12205 (PHLH8_24080) 2619480..2620031 - 552 WP_213630521.1 chalcone isomerase family protein -
PHLH3_RS12210 (PHLH8_24090) 2620263..2621219 + 957 WP_173174505.1 helix-turn-helix domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

5'-deoxynucleotidase YfbR/HDDC2

(7-178)

Antitoxin

Cro/C1-type helix-turn-helix domain

(12-67)


Sequences

Toxin        


Download         Length: 195 a.a.        Molecular weight: 21573.20 Da        Isoelectric Point: 4.6874

>T33691 WP_213629469.1 NZ_AP021905:2615723-2616307 [Pseudomonas sp. Pc102]
MNIDTIRARLDFLREAERLKDVLRSAHTSSGRAESTAEHSWRLCLMAITFADELAGLDLLRVLKMCVVHDLGEAIHGDIP
AVEQGGHPDKGAQEREDLLTLTRTLDDGLRGEILALWDDYENAASPEALAVKALDKLETLLQHTQGANPEDFDYAFNLGY
GRRYTSGEPLFAAIRAQLDEDTRRRMEAQAGAAR

Download         Length: 585 bp

>T33691 NZ_AP021905:2615723-2616307 [Pseudomonas sp. Pc102]
ATGAACATCGACACCATCAGGGCGCGGCTCGACTTCCTGCGTGAGGCGGAGCGCCTCAAGGATGTGCTGCGCAGCGCCCA
CACCTCTTCCGGGCGGGCGGAAAGCACCGCCGAGCACAGCTGGCGCCTGTGCCTGATGGCCATCACCTTCGCCGACGAGC
TGGCCGGGCTCGACCTGCTGCGGGTGCTGAAGATGTGCGTGGTGCACGACCTGGGCGAGGCCATCCATGGCGACATCCCC
GCCGTCGAGCAGGGCGGCCATCCCGACAAGGGGGCCCAGGAGCGCGAGGACCTGCTGACCCTCACCCGCACCCTGGACGA
TGGGCTGCGCGGGGAGATCCTCGCGCTGTGGGACGACTACGAGAACGCCGCCTCCCCCGAGGCGCTGGCGGTCAAGGCGC
TGGACAAGCTGGAGACCCTGCTGCAGCACACCCAGGGCGCCAACCCGGAGGACTTCGACTACGCCTTCAACCTCGGCTAC
GGGCGCCGCTACACCAGCGGCGAACCGCTGTTCGCGGCCATCCGTGCACAGCTGGACGAGGACACGAGGCGGCGGATGGA
GGCGCAGGCGGGCGCGGCTCGCTGA

Antitoxin


Download         Length: 186 a.a.        Molecular weight: 20272.47 Da        Isoelectric Point: 9.3330

>AT33691 WP_213629468.1 NZ_AP021905:2615054-2615611 [Pseudomonas sp. Pc102]
MYDSLPKPISLGLALRRWRLLHRVKQAHAAQLFGVAQSTISRWESGAQAMEPAERARVEQVLGARLEAAADQALARLVGD
SPRAVHLVCDLSHRLLACSALRAAEFGVPLSELLGRSLWRYATPEIVRKEAALDALGWRDVLMPPALEFGSGSNESAIVP
IRQGLCRWTRMTLSDGTAARLVETL

Download         Length: 558 bp

>AT33691 NZ_AP021905:2615054-2615611 [Pseudomonas sp. Pc102]
ATGTACGACAGCCTCCCGAAACCGATCTCGCTCGGCCTCGCGTTGCGCCGTTGGCGCCTGCTGCACCGGGTGAAGCAGGC
CCACGCCGCGCAGCTGTTCGGCGTCGCCCAGTCGACCATCTCGCGCTGGGAAAGCGGGGCGCAGGCGATGGAGCCGGCCG
AGCGCGCGCGGGTGGAGCAGGTGCTTGGCGCCCGGCTGGAGGCGGCGGCCGACCAGGCCCTGGCGCGGCTGGTGGGCGAC
AGCCCGCGCGCGGTGCACCTGGTCTGCGACCTGAGCCATCGCCTGCTGGCCTGTTCCGCCCTGCGCGCCGCCGAATTCGG
CGTGCCCCTCTCCGAGCTGCTGGGCCGCTCGCTGTGGCGCTACGCGACGCCGGAGATCGTGCGCAAGGAAGCCGCGCTGG
ACGCCCTGGGCTGGCGCGACGTGCTGATGCCGCCGGCGCTGGAGTTCGGCAGCGGCAGCAACGAATCCGCCATCGTACCG
ATCCGCCAGGGCCTGTGCCGCTGGACGCGCATGACGCTTTCCGACGGCACCGCCGCGCGCCTGGTGGAAACCCTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References