Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1937494..1937765 Replicon chromosome
Accession NZ_AP021895
Organism Escherichia coli strain 2018-11-3CC

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1937624..1937727 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1937494..1937765 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HRR26_RS09235 1934049..1934711 - 663 WP_000944256.1 exodeoxyribonuclease X -
HRR26_RS09240 1934735..1935391 - 657 WP_000011657.1 carbon-nitrogen hydrolase family protein -
HRR26_RS09245 1935493..1935723 - 231 WP_000916763.1 DNA polymerase III subunit theta -
HRR26_RS09250 1935862..1936236 + 375 WP_000168747.1 CopC domain-containing protein YobA -
HRR26_RS09255 1936240..1937112 + 873 WP_000879298.1 copper homeostasis membrane protein CopD -
HRR26_RS09260 1937125..1937466 + 342 WP_000976472.1 YebY family protein -
- 1937494..1937765 - 272 - - Antitoxin
- 1937624..1937727 + 104 - - Toxin
HRR26_RS09265 1937862..1938518 + 657 WP_000812733.1 protein-serine/threonine phosphatase -
HRR26_RS09270 1938519..1938710 - 192 WP_001338167.1 YebW family protein -
HRR26_RS09275 1938815..1939051 - 237 WP_001338166.1 DUF1480 family protein -
HRR26_RS09280 1939169..1940608 - 1440 WP_024238487.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T33638 NZ_AP021895:1937624-1937727 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT33638 NZ_AP021895:c1937765-1937494 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References