Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 266085..266356 Replicon chromosome
Accession NZ_AP021892
Organism Escherichia coli strain 2018-01-1CC

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 266215..266318 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 266085..266356 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HRR21_RS01305 262640..263302 - 663 WP_000944256.1 exodeoxyribonuclease X -
HRR21_RS01310 263326..263982 - 657 WP_000011657.1 carbon-nitrogen hydrolase family protein -
HRR21_RS01315 264084..264314 - 231 WP_000916763.1 DNA polymerase III subunit theta -
HRR21_RS01320 264453..264827 + 375 WP_000168747.1 CopC domain-containing protein YobA -
HRR21_RS01325 264831..265703 + 873 WP_000879298.1 copper homeostasis membrane protein CopD -
HRR21_RS01330 265716..266057 + 342 WP_000976472.1 YebY family protein -
- 266085..266356 - 272 - - Antitoxin
- 266215..266318 + 104 - - Toxin
HRR21_RS01335 266453..267109 + 657 WP_170888251.1 protein-serine/threonine phosphatase -
HRR21_RS01340 267110..267301 - 192 WP_001338167.1 YebW family protein -
HRR21_RS01345 267406..267642 - 237 WP_001338166.1 DUF1480 family protein -
HRR21_RS01350 267760..269199 - 1440 WP_024238487.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T33569 NZ_AP021892:266215-266318 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT33569 NZ_AP021892:c266356-266085 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References