Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1939926..1940197 Replicon chromosome
Accession NZ_AP021891
Organism Escherichia coli strain 2017.01.04CC

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1940056..1940159 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1939926..1940197 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
VEGS_RS09250 1936481..1937143 - 663 WP_124038297.1 exodeoxyribonuclease X -
VEGS_RS09255 1937167..1937823 - 657 WP_172409713.1 carbon-nitrogen hydrolase family protein -
VEGS_RS09260 1937925..1938155 - 231 WP_000916763.1 DNA polymerase III subunit theta -
VEGS_RS09265 1938294..1938668 + 375 WP_000168747.1 CopC domain-containing protein YobA -
VEGS_RS09270 1938672..1939544 + 873 WP_000879298.1 copper homeostasis membrane protein CopD -
VEGS_RS09275 1939557..1939898 + 342 WP_124038296.1 YebY family protein -
- 1939926..1940197 - 272 - - Antitoxin
- 1940056..1940159 + 104 - - Toxin
VEGS_RS09280 1940294..1940950 + 657 WP_000812733.1 protein-serine/threonine phosphatase -
VEGS_RS09285 1940951..1941142 - 192 WP_001338167.1 YebW family protein -
VEGS_RS09290 1941247..1941483 - 237 WP_001338166.1 DUF1480 family protein -
VEGS_RS09295 1941601..1943040 - 1440 WP_024238487.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T33553 NZ_AP021891:1940056-1940159 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT33553 NZ_AP021891:c1940197-1939926 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References