Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2641962..2642233 Replicon chromosome
Accession NZ_AP021890
Organism Escherichia coli strain 2017.15.01CC

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2642000..2642103 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2641962..2642233 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HRR22_RS12515 2639119..2640558 + 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
HRR22_RS12520 2640676..2640912 + 237 WP_001295499.1 DUF1480 family protein -
HRR22_RS12525 2641017..2641208 + 192 WP_001296140.1 YebW family protein -
HRR22_RS12530 2641209..2641865 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 2641962..2642233 + 272 - - Antitoxin
- 2642000..2642103 - 104 - - Toxin
HRR22_RS12535 2642261..2642602 - 342 WP_000976492.1 YebY family protein -
HRR22_RS12540 2642615..2643487 - 873 WP_000879280.1 copper homeostasis membrane protein CopD -
HRR22_RS12545 2643491..2643865 - 375 WP_000204699.1 CopC domain-containing protein YobA -
HRR22_RS12550 2644004..2644234 + 231 WP_000916763.1 DNA polymerase III subunit theta -
HRR22_RS12555 2644336..2644992 + 657 WP_000011652.1 carbon-nitrogen hydrolase family protein -
HRR22_RS12560 2645016..2645678 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T33530 NZ_AP021890:c2642103-2642000 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT33530 NZ_AP021890:2641962-2642233 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCTTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References