Detailed information of TA system TA033518

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE(toxin)
• Location: 1824639..1825101
• Replicon: chromosome
• Accession: NZ_AP021889
• Organism: Thiosulfatimonas sediminis strain aks77

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: HRR27_RS08515
• Protein ID: WP_173272787.1
• Coordinates: 1824639..1824923 (-)
• Length: 95 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: HRR27_RS08520
• Protein ID: WP_197905452.1
• Coordinates: 1824913..1825101 (-)
• Length: 63 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HRR27_RS08470	1819860..1820234	-	375	WP_173272769.1	hypothetical protein	-
HRR27_RS08475	1820245..1820658	-	414	WP_173272771.1	hypothetical protein	-
HRR27_RS08480	1820843..1821496	+	654	WP_173272773.1	hypothetical protein	-
HRR27_RS08485	1821493..1821708	+	216	WP_173272775.1	hypothetical protein	-
HRR27_RS08490	1821872..1822069	-	198	WP_173272777.1	hypothetical protein	-
HRR27_RS08495	1822590..1822886	-	297	WP_173272779.1	type II toxin-antitoxin system RelE/ParE family toxin	-
HRR27_RS08500	1822907..1823146	-	240	WP_173272781.1	type II toxin-antitoxin system ParD family antitoxin	-
HRR27_RS08505	1823233..1823676	-	444	WP_173272783.1	hypothetical protein	-
HRR27_RS08510	1824213..1824404	-	192	WP_173272785.1	hypothetical protein	-
HRR27_RS08515	1824639..1824923	-	285	WP_173272787.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
HRR27_RS08520	1824913..1825101	-	189	WP_197905452.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
HRR27_RS08525	1825310..1825723	+	414	WP_173272789.1	hypothetical protein	-
HRR27_RS08530	1825767..1827524	-	1758	WP_173272791.1	conjugal transfer protein TraG N-terminal domain-containing protein	-
HRR27_RS08535	1827536..1828903	-	1368	WP_173272793.1	hypothetical protein	-
HRR27_RS08540	1828900..1829415	-	516	WP_173272795.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Integrative and Conjugative Element	-	-	1810350..1864108	53758

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-84)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 95 a.a.
• Molecular weight: 10887.66 Da
• Isoelectric Point: 10.4241

>T33518 WP_173272787.1 NZ_AP021889:c1824923-1824639 [Thiosulfatimonas sediminis]
MSYSLTFKDSALKEWGKLDATVKEAFRKKLKERLENPHVESAKLNGLNDCYKIKLRSVGYRLVYQVRDNELVVSVIAVGK
RDRNQVYKAAINRI

Nucleotide

• Length: 285 bp

>T33518 NZ_AP021889:c1824923-1824639 [Thiosulfatimonas sediminis]
ATGAGCTATAGCCTTACTTTCAAAGATTCCGCTTTGAAGGAGTGGGGAAAGCTTGATGCGACCGTTAAAGAAGCGTTTCG
CAAAAAGCTGAAAGAACGACTTGAGAATCCTCATGTTGAGTCAGCGAAGCTAAATGGTCTGAATGACTGCTACAAAATCA
AATTACGCAGTGTGGGTTATCGCCTGGTATACCAAGTGCGAGACAATGAATTGGTGGTTTCCGTGATCGCTGTCGGCAAA
AGAGACCGTAACCAAGTTTACAAAGCCGCTATAAATCGAATCTAA

Antitoxin

Protein

• Length: 63 a.a.
• Molecular weight: 7024.96 Da
• Isoelectric Point: 3.9330

>AT33518 WP_197905452.1 NZ_AP021889:c1825101-1824913 [Thiosulfatimonas sediminis]
MAVLQQGEGFPVAILNRNQPVFYAVPAKAYEQLLDRIEDLELAALVRERQDEPEVSVNLDEL

Nucleotide

• Length: 189 bp

>AT33518 NZ_AP021889:c1825101-1824913 [Thiosulfatimonas sediminis]
ATGGCGGTGCTTCAGCAAGGTGAAGGGTTTCCGGTGGCGATTTTAAATCGTAATCAACCGGTGTTTTATGCTGTGCCGGC
AAAAGCCTATGAACAGCTGCTCGATAGAATCGAAGATTTGGAGTTAGCGGCTTTGGTTCGAGAGCGTCAAGATGAGCCAG
AAGTTTCGGTTAATCTTGATGAGCTATAG