Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 582342..582861 Replicon chromosome
Accession NZ_AP021889
Organism Thiosulfatimonas sediminis strain aks77

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HRR27_RS02615 Protein ID WP_173270502.1
Coordinates 582342..582632 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HRR27_RS02620 Protein ID WP_173270505.1
Coordinates 582622..582861 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HRR27_RS02585 577743..578615 + 873 WP_173270482.1 YihY family inner membrane protein -
HRR27_RS02590 578608..579606 + 999 WP_173270485.1 iron ABC transporter permease -
HRR27_RS02595 579606..580427 + 822 WP_173270489.1 ATP-binding cassette domain-containing protein -
HRR27_RS02600 580499..580759 + 261 WP_173270493.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
HRR27_RS02605 580756..581019 + 264 WP_173270496.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family -
HRR27_RS02610 581128..582270 - 1143 WP_173270499.1 HprK-related kinase B -
HRR27_RS02615 582342..582632 - 291 WP_173270502.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HRR27_RS02620 582622..582861 - 240 WP_173270505.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
HRR27_RS02625 583013..583921 - 909 WP_173270508.1 GAK system ATP-grasp enzyme -
HRR27_RS02630 583914..585542 - 1629 WP_173270511.1 aminoglycoside phosphotransferase family protein -
HRR27_RS02635 585588..585887 - 300 WP_173270514.1 amphi-Trp domain-containing protein -
HRR27_RS02640 585930..587153 - 1224 WP_173270518.1 metallophosphoesterase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-81)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-72)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11540.45 Da        Isoelectric Point: 10.3950

>T33516 WP_173270502.1 NZ_AP021889:c582632-582342 [Thiosulfatimonas sediminis]
MTYSLEFDERALKEWKQLDGSIRSQLKKKLEKVIENPKVKKNELRELDNCYKIKLRQSGYRLIYQVQDARVVVFVVAIGK
RDKERAYRDATYRIKT

Download         Length: 291 bp

>T33516 NZ_AP021889:c582632-582342 [Thiosulfatimonas sediminis]
ATGACTTATAGCCTTGAATTTGATGAACGCGCACTCAAGGAATGGAAACAACTGGATGGGAGTATTCGTAGCCAATTAAA
AAAGAAACTTGAGAAGGTTATTGAGAACCCAAAAGTTAAGAAGAATGAACTTAGAGAGCTTGATAATTGTTACAAAATCA
AATTACGTCAAAGTGGCTATCGATTGATTTATCAAGTACAAGATGCCCGTGTAGTGGTGTTTGTTGTTGCAATTGGTAAA
CGTGATAAAGAACGGGCTTATCGAGATGCGACATACCGAATAAAAACATAA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9017.22 Da        Isoelectric Point: 4.1232

>AT33516 WP_173270505.1 NZ_AP021889:c582861-582622 [Thiosulfatimonas sediminis]
MGTITIRVDDNLKSEAYQALEDLNITPSELLRQTLEYVAQNHKLPFKPVLLNDEDLDLLETVRERLNDPKPVAVSLDDL

Download         Length: 240 bp

>AT33516 NZ_AP021889:c582861-582622 [Thiosulfatimonas sediminis]
ATGGGAACTATCACAATTAGAGTTGACGACAATCTTAAAAGCGAAGCCTACCAAGCCTTAGAAGACTTAAACATCACTCC
GTCAGAGTTATTACGTCAAACTTTAGAATACGTAGCTCAAAACCATAAACTTCCATTTAAACCCGTGCTTTTAAATGATG
AAGATTTAGATTTATTGGAAACCGTTCGTGAGCGTTTAAATGACCCTAAGCCTGTTGCGGTGAGTTTGGATGACTTATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References