Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 2602030..2602666 Replicon chromosome
Accession NZ_AP021888
Organism Thiosulfativibrio zosterae strain AkT22

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag THMIRH_RS11890 Protein ID WP_173292303.1
Coordinates 2602265..2602666 (+) Length 134 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag THMIRH_RS11885 Protein ID WP_194240842.1
Coordinates 2602030..2602272 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
THMIRH_RS11865 2597204..2598181 - 978 WP_173292299.1 ABC transporter substrate-binding protein -
THMIRH_RS11870 2598316..2598522 + 207 WP_173292300.1 hypothetical protein -
THMIRH_RS11875 2598600..2601434 + 2835 WP_173292301.1 EAL domain-containing protein -
THMIRH_RS11880 2601444..2601920 + 477 WP_173292302.1 hypothetical protein -
THMIRH_RS11885 2602030..2602272 + 243 WP_194240842.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
THMIRH_RS11890 2602265..2602666 + 402 WP_173292303.1 type II toxin-antitoxin system VapC family toxin Toxin
THMIRH_RS11895 2602831..2603352 + 522 WP_173292304.1 transposase -
THMIRH_RS11900 2603626..2604228 - 603 WP_173292305.1 LPP20 family lipoprotein -
THMIRH_RS11905 2604641..2607346 + 2706 WP_173292306.1 response regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 14992.32 Da        Isoelectric Point: 7.4335

>T33515 WP_173292303.1 NZ_AP021888:2602265-2602666 [Thiosulfativibrio zosterae]
MIKYLLDTNICIYVIKRRPIEVLQKFNEAAGHIAISSITLAELLHGVEKSQHLAKNLKAVEDFCSRLDVLNYDDKAASHY
GEIRADLEKKGKPIGVNDLHIAGHARSMGAILVSNNLKEFERVEGLRLQNWID

Download         Length: 402 bp

>T33515 NZ_AP021888:2602265-2602666 [Thiosulfativibrio zosterae]
ATGATTAAATATTTATTGGACACCAACATATGTATTTATGTCATCAAACGCCGACCCATAGAAGTTTTACAAAAATTTAA
TGAGGCGGCAGGTCATATCGCCATTTCCTCTATTACACTTGCTGAACTCTTGCATGGCGTTGAAAAAAGCCAACATCTTG
CCAAAAACCTCAAAGCAGTTGAAGATTTTTGCAGTCGATTAGATGTGCTCAACTATGACGACAAAGCTGCTTCGCATTAT
GGTGAGATTCGGGCAGATTTAGAGAAAAAAGGCAAACCGATTGGTGTTAATGATTTGCATATAGCTGGTCATGCCAGAAG
TATGGGTGCAATTCTTGTGAGTAATAACCTAAAAGAGTTTGAGCGAGTTGAAGGCTTACGGCTTCAAAACTGGATTGACT
AA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9070.23 Da        Isoelectric Point: 4.7405

>AT33515 WP_194240842.1 NZ_AP021888:2602030-2602272 [Thiosulfativibrio zosterae]
MINATVFENNKTQAVRLPVAVRFPSSVKKVVVRAVGKERVICPLENTWDSFFLNPETAVSDDFLNERAQQTESPREAFDD

Download         Length: 243 bp

>AT33515 NZ_AP021888:2602030-2602272 [Thiosulfativibrio zosterae]
ATGATTAATGCAACCGTTTTTGAAAATAATAAAACCCAAGCCGTTCGCTTACCTGTTGCCGTGCGCTTTCCCAGCTCCGT
TAAAAAAGTGGTTGTGCGCGCAGTTGGTAAAGAACGCGTGATTTGCCCACTTGAAAACACTTGGGATAGTTTCTTTTTAA
ATCCAGAAACCGCTGTTTCAGATGATTTTTTGAATGAGCGTGCCCAACAAACCGAAAGCCCAAGAGAAGCTTTTGATGAT
TAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References