Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-RelB
Location 1376255..1376768 Replicon chromosome
Accession NZ_AP021888
Organism Thiosulfativibrio zosterae strain AkT22

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag THMIRH_RS06310 Protein ID WP_173291289.1
Coordinates 1376502..1376768 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag THMIRH_RS06305 Protein ID WP_173291288.1
Coordinates 1376255..1376512 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
THMIRH_RS06280 1371534..1373522 - 1989 WP_173291283.1 monovalent cation:proton antiporter family protein -
THMIRH_RS06285 1373528..1374394 - 867 WP_173291284.1 carboxylating nicotinate-nucleotide diphosphorylase -
THMIRH_RS06290 1374488..1375081 + 594 WP_173291285.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
THMIRH_RS06295 1375078..1375305 - 228 WP_173291286.1 uracil-DNA glycosylase -
THMIRH_RS06300 1375470..1375985 + 516 WP_173291287.1 flavodoxin FldA -
THMIRH_RS06305 1376255..1376512 + 258 WP_173291288.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
THMIRH_RS06310 1376502..1376768 + 267 WP_173291289.1 Txe/YoeB family addiction module toxin Toxin
THMIRH_RS06315 1376860..1379439 - 2580 WP_173291290.1 ATP-dependent helicase HrpB -
THMIRH_RS06320 1379461..1380042 - 582 WP_173291291.1 hypothetical protein -
THMIRH_RS06325 1380055..1380900 - 846 WP_173291292.1 MYG1 family protein -
THMIRH_RS06330 1380978..1381445 - 468 WP_173291293.1 flagellar basal body-associated FliL family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(8-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10518.00 Da        Isoelectric Point: 6.9478

>T33514 WP_173291289.1 NZ_AP021888:1376502-1376768 [Thiosulfativibrio zosterae]
MKIEILSWTECAWSDYLYWQTQDKKTLKRINKLITDAMRSPFEGIGKPEPLKENLSGFWSRRIDESNRLVYAVDDNQITI
IACRYHYD

Download         Length: 267 bp

>T33514 NZ_AP021888:1376502-1376768 [Thiosulfativibrio zosterae]
ATGAAGATTGAAATTCTCTCTTGGACTGAATGTGCCTGGAGCGATTATCTTTACTGGCAAACTCAAGACAAAAAAACGCT
TAAACGAATTAACAAACTCATTACTGATGCAATGCGTTCGCCATTTGAAGGAATCGGTAAGCCTGAACCATTAAAAGAAA
ACCTTTCAGGATTTTGGTCAAGACGCATAGATGAGTCAAATCGACTTGTTTATGCGGTTGATGATAACCAGATAACGATA
ATCGCTTGCCGATACCACTACGATTGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9438.67 Da        Isoelectric Point: 4.9878

>AT33514 WP_173291288.1 NZ_AP021888:1376255-1376512 [Thiosulfativibrio zosterae]
MQVVSYTDARNSLKSVLDSVVDNVDVTIITRRDADNAVVMSQDYFNSLMETVHLLKSPANVAHLKESIAQYRSGKTIPKG
LIDED

Download         Length: 258 bp

>AT33514 NZ_AP021888:1376255-1376512 [Thiosulfativibrio zosterae]
ATGCAAGTTGTAAGCTATACAGACGCAAGAAACAGTCTAAAAAGCGTATTGGATTCTGTTGTCGATAATGTTGATGTCAC
AATCATTACACGTCGGGATGCTGATAACGCGGTAGTGATGTCTCAAGACTATTTTAATAGCCTAATGGAAACGGTACATT
TATTGAAATCGCCTGCCAATGTGGCGCACCTGAAAGAATCTATTGCACAGTATCGTTCAGGCAAAACCATCCCAAAAGGT
TTAATTGATGAAGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References