Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 2779502..2780139 Replicon chromosome
Accession NZ_AP021884
Organism Sulfuriferula plumbiphila strain Gro7

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag GZH91_RS14360 Protein ID WP_147070254.1
Coordinates 2779738..2780139 (+) Length 134 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag GZH91_RS14355 Protein ID WP_147070255.1
Coordinates 2779502..2779732 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GZH91_RS14345 2776810..2777289 + 480 WP_147070259.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
GZH91_RS14350 2777383..2779350 + 1968 WP_161984289.1 O-antigen ligase family protein -
GZH91_RS14355 2779502..2779732 + 231 WP_147070255.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
GZH91_RS14360 2779738..2780139 + 402 WP_147070254.1 type II toxin-antitoxin system VapC family toxin Toxin
GZH91_RS14365 2780157..2780837 - 681 WP_147070252.1 energy transducer TonB -
GZH91_RS14370 2780830..2781231 - 402 WP_147070250.1 biopolymer transporter ExbD -
GZH91_RS14375 2781228..2781881 - 654 WP_147070248.1 MotA/TolQ/ExbB proton channel family protein -
GZH91_RS14380 2781924..2784275 - 2352 WP_147070246.1 TonB-dependent receptor -
GZH91_RS14385 2784353..2784667 - 315 WP_147070244.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-122)

Antitoxin

SpoVT-AbrB domain

(7-43)


Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 14399.39 Da        Isoelectric Point: 5.5168

>T33509 WP_147070254.1 NZ_AP021884:2779738-2780139 [Sulfuriferula plumbiphila]
MHYMLDTNICIYAIKNRPAQVLTHLRAHETAGIGISSISVAELYFGVAKSGSARNLTALQQFLEPLEIADFDVSAAQAYG
TLRYTLERSGTPIGPLDTQIAAHALALGATLVTNNGLEFARVPDLNWINWAAE

Download         Length: 402 bp

>T33509 NZ_AP021884:2779738-2780139 [Sulfuriferula plumbiphila]
ATGCATTACATGCTCGACACCAACATCTGCATCTACGCCATCAAGAATCGGCCCGCACAGGTACTCACACATCTGCGTGC
TCATGAAACGGCAGGGATAGGCATATCCAGCATCAGCGTGGCTGAACTGTATTTTGGCGTTGCCAAAAGCGGCTCAGCCA
GAAATCTGACTGCGTTGCAGCAATTCCTGGAGCCACTGGAAATCGCCGACTTCGACGTAAGCGCAGCGCAGGCCTATGGC
ACGCTGCGCTACACGCTTGAACGGTCGGGCACTCCCATTGGCCCGCTGGATACACAAATTGCGGCGCATGCTCTGGCACT
GGGGGCGACGCTGGTGACGAACAATGGCCTGGAATTTGCCCGTGTGCCCGACCTGAACTGGATAAACTGGGCGGCGGAAT
AA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8720.96 Da        Isoelectric Point: 5.0807

>AT33509 WP_147070255.1 NZ_AP021884:2779502-2779732 [Sulfuriferula plumbiphila]
MQTAKLFINGRSQAVRLPKAFRFEGVQEVLIERVGDAVILRPPKRPSIEQLIAALDQFESFPEREQPDTADTRDPW

Download         Length: 231 bp

>AT33509 NZ_AP021884:2779502-2779732 [Sulfuriferula plumbiphila]
ATGCAAACCGCCAAATTGTTCATCAATGGCCGCAGCCAGGCTGTGCGCCTGCCCAAGGCCTTTCGTTTTGAAGGTGTGCA
GGAAGTGTTAATTGAGCGCGTCGGAGATGCTGTGATACTACGCCCACCCAAACGCCCGTCGATTGAACAGCTGATTGCCG
CATTGGATCAGTTCGAGTCGTTTCCCGAGCGGGAACAACCCGATACTGCCGACACGCGCGATCCCTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References