Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 1062497..1063001 Replicon chromosome
Accession NZ_AP021884
Organism Sulfuriferula plumbiphila strain Gro7

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag GZH91_RS05675 Protein ID WP_147073963.1
Coordinates 1062497..1062751 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag GZH91_RS05680 Protein ID WP_147073965.1
Coordinates 1062741..1063001 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GZH91_RS05650 1059769..1060221 + 453 WP_147073955.1 type IV pilin protein -
GZH91_RS05655 1060343..1060778 - 436 Protein_1101 hypothetical protein -
GZH91_RS05660 1060791..1061054 + 264 WP_198415461.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
GZH91_RS05665 1061056..1061481 + 426 WP_147073959.1 type II toxin-antitoxin system VapC family toxin -
GZH91_RS05670 1061530..1062477 - 948 WP_147073961.1 4-hydroxy-3-methylbut-2-enyl diphosphate reductase -
GZH91_RS05675 1062497..1062751 - 255 WP_147073963.1 Txe/YoeB family addiction module toxin Toxin
GZH91_RS05680 1062741..1063001 - 261 WP_147073965.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
GZH91_RS05685 1063061..1063516 - 456 WP_147073967.1 FKBP-type peptidyl-prolyl cis-trans isomerase -
GZH91_RS05690 1063513..1063983 - 471 WP_147073970.1 lipoprotein signal peptidase -
GZH91_RS05695 1063976..1066747 - 2772 WP_147073971.1 isoleucine--tRNA ligase -
GZH91_RS05700 1066740..1067699 - 960 WP_147073973.1 bifunctional riboflavin kinase/FAD synthetase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10033.41 Da        Isoelectric Point: 8.4985

>T33507 WP_147073963.1 NZ_AP021884:c1062751-1062497 [Sulfuriferula plumbiphila]
MQIRFAEQGRQDYIYWQQTDKAALRRINTLIHDITRSPFDGIGKPEPLRHNLAGFWSRRISDEHRLVYAIEDGCLLIAQC
RYHY

Download         Length: 255 bp

>T33507 NZ_AP021884:c1062751-1062497 [Sulfuriferula plumbiphila]
ATGCAGATTAGATTTGCTGAACAAGGTCGGCAGGATTACATCTATTGGCAGCAAACAGATAAAGCGGCACTCAGGCGCAT
CAATACGCTCATCCATGACATAACGCGTTCACCTTTCGATGGCATCGGAAAACCCGAACCGCTACGCCACAATCTGGCTG
GATTCTGGTCACGCAGGATTAGCGATGAGCATCGCCTGGTTTATGCAATCGAGGATGGCTGTCTGCTGATCGCCCAATGC
CGCTATCATTACTAA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9533.87 Da        Isoelectric Point: 5.5648

>AT33507 WP_147073965.1 NZ_AP021884:c1063001-1062741 [Sulfuriferula plumbiphila]
MDAISYSYTRQHFADVMDKVNDDCAPVLVTRQNGKPVVMMSLAHFNALEETAYLLRSPENARRLMAAVAELRSGAGVKHE
LLPDAD

Download         Length: 261 bp

>AT33507 NZ_AP021884:c1063001-1062741 [Sulfuriferula plumbiphila]
ATGGATGCCATCAGCTACAGCTATACACGCCAGCACTTTGCCGATGTGATGGACAAAGTGAATGACGATTGCGCGCCGGT
TCTGGTTACGCGCCAGAATGGCAAACCGGTGGTGATGATGTCGCTCGCGCATTTCAACGCACTGGAAGAGACTGCATACC
TGCTGCGCAGCCCGGAAAACGCGCGCCGTCTGATGGCTGCAGTGGCGGAATTAAGAAGTGGTGCGGGCGTCAAACACGAG
CTGCTGCCTGATGCAGATTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References