Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 3310325..3310913 Replicon chromosome
Accession NZ_AP021881
Organism Sulfuriferula nivalis strain SGTM

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag SFSGTM_RS16325 Protein ID WP_162086389.1
Coordinates 3310325..3310621 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag SFSGTM_RS16330 Protein ID WP_162086085.1
Coordinates 3310623..3310913 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SFSGTM_RS16305 3306736..3306957 - 222 WP_162086081.1 nicotinamide mononucleotide transporter -
SFSGTM_RS16310 3307198..3307536 + 339 WP_162086082.1 hypothetical protein -
SFSGTM_RS16315 3307729..3309030 + 1302 WP_162086083.1 hypothetical protein -
SFSGTM_RS16320 3309252..3309827 - 576 WP_162086084.1 recombinase family protein -
SFSGTM_RS16325 3310325..3310621 + 297 WP_162086389.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
SFSGTM_RS16330 3310623..3310913 + 291 WP_162086085.1 putative addiction module antidote protein Antitoxin
SFSGTM_RS16335 3311211..3312389 - 1179 WP_162086086.1 polysaccharide deacetylase family protein -
SFSGTM_RS16340 3312389..3313573 - 1185 WP_162086087.1 tetratricopeptide repeat protein -
SFSGTM_RS16345 3314284..3314625 - 342 WP_162086390.1 antibiotic biosynthesis monooxygenase -
SFSGTM_RS16350 3314666..3314959 - 294 WP_162086088.1 DUF1330 domain-containing protein -
SFSGTM_RS16355 3314992..3315129 + 138 WP_162085929.1 hypothetical protein -
SFSGTM_RS16360 3315283..3315774 - 492 WP_162085930.1 thiol peroxidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 3309252..3309827 575


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-95)

Antitoxin

Uncharacterized protein HI1420

(3-92)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11125.80 Da        Isoelectric Point: 10.1398

>T33497 WP_162086389.1 NZ_AP021881:3310325-3310621 [Sulfuriferula nivalis]
MVEIKQTETFRRWRTHLKDERARALIASRLDRLSFGHAGDVAPVGQGISELRIHYGPGYRVYFHKRGDKIIVLLCGGDKS
TQAKDIKTAKCLAAEWSE

Download         Length: 297 bp

>T33497 NZ_AP021881:3310325-3310621 [Sulfuriferula nivalis]
ATGGTTGAGATAAAACAAACAGAGACTTTCCGACGATGGCGAACACATCTCAAAGATGAGCGTGCTCGTGCTCTGATTGC
ATCCCGTTTGGACCGCCTTAGCTTCGGTCATGCAGGGGATGTAGCACCTGTGGGACAAGGGATTAGCGAATTACGTATTC
ATTATGGTCCTGGATACCGCGTCTATTTCCACAAACGAGGTGACAAAATCATCGTCTTGCTGTGTGGTGGAGATAAGAGC
ACACAGGCAAAAGATATTAAGACTGCAAAATGTTTAGCTGCTGAATGGAGTGAATGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10328.70 Da        Isoelectric Point: 5.0495

>AT33497 WP_162086085.1 NZ_AP021881:3310623-3310913 [Sulfuriferula nivalis]
MAEKLTTYDPAEDLSSDEAMATFMAEAFETNDASYIAHSIGVVARAKGMAEIAGKTGLSREQLYRSFSNNGNPTLKTTLA
VMKSLGLDLTAKIHQI

Download         Length: 291 bp

>AT33497 NZ_AP021881:3310623-3310913 [Sulfuriferula nivalis]
ATGGCTGAAAAACTTACCACCTATGATCCCGCTGAAGATTTATCTTCTGATGAAGCGATGGCGACCTTTATGGCTGAAGC
CTTCGAGACAAACGATGCCAGTTACATCGCGCACTCAATTGGTGTGGTTGCACGTGCAAAGGGTATGGCCGAGATTGCTG
GCAAAACAGGTCTTTCTCGAGAGCAACTTTATCGCTCTTTTAGCAACAATGGCAACCCAACTCTGAAAACCACCCTTGCT
GTGATGAAGTCTCTTGGTCTCGATCTGACGGCTAAGATCCATCAAATTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References