Detailed information of TA system TA033493

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relE-dinJ/YafQ-RelB
• Location: 3099879..3100410
• Replicon: chromosome
• Accession: NZ_AP021881
• Organism: Sulfuriferula nivalis strain SGTM

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: SFSGTM_RS15265
• Protein ID: WP_162085906.1
• Coordinates: 3100129..3100410 (+)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: dinJ
• Uniprot ID: -
• Locus tag: SFSGTM_RS15260
• Protein ID: WP_162085905.1
• Coordinates: 3099879..3100142 (+)
• Length: 88 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SFSGTM_RS15255	3095867..3099403	+	3537	WP_162085904.1	DUF748 domain-containing protein	-
SFSGTM_RS15260	3099879..3100142	+	264	WP_162085905.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
SFSGTM_RS15265	3100129..3100410	+	282	WP_162085906.1	type II toxin-antitoxin system YafQ family toxin	Toxin
SFSGTM_RS15270	3100535..3100807	-	273	WP_162085907.1	HU family DNA-binding protein	-
SFSGTM_RS15275	3101048..3101584	+	537	WP_162085908.1	DUF4337 domain-containing protein	-
SFSGTM_RS15280	3101874..3105341	+	3468	WP_198420571.1	type VI secretion system tip protein VgrG	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, YafQ-like toxin (2-91)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (4-77)

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 10754.30 Da
• Isoelectric Point: 9.7203

>T33493 WP_162085906.1 NZ_AP021881:3100129-3100410 [Sulfuriferula nivalis]
MRKIDPTSQFRRDYKREAKGQHRVTLDADLAPVLQTLANDQPLAPRHRDHALTGDWKEHRDCHIKPDLVLIYRKPDAVTL
QLIRIGSHSELGL

Nucleotide

• Length: 282 bp

>T33493 NZ_AP021881:3100129-3100410 [Sulfuriferula nivalis]
ATGCGGAAGATTGATCCGACCAGTCAGTTCAGGCGTGATTACAAACGCGAAGCAAAAGGTCAGCATCGCGTAACGCTCGA
TGCTGATTTAGCACCCGTACTCCAGACACTGGCCAACGATCAGCCATTAGCGCCGCGCCATCGTGACCATGCGCTTACTG
GCGACTGGAAAGAACATCGAGATTGCCACATTAAGCCAGATTTGGTATTGATTTACCGAAAGCCAGATGCTGTCACCCTG
CAACTCATACGAATTGGCTCGCACAGTGAGCTGGGTCTTTAA

Antitoxin

Protein

• Length: 88 a.a.
• Molecular weight: 9555.00 Da
• Isoelectric Point: 4.7914

>AT33493 WP_162085905.1 NZ_AP021881:3099879-3100142 [Sulfuriferula nivalis]
MTTNAVVRARIDEHIKEEASIVLATMGLTVSDAFRIMLTRIAREKALPFDPLVPNETTIAAMREARAGNLKSFDSVDALM
ADLHAED

Nucleotide

• Length: 264 bp

>AT33493 NZ_AP021881:3099879-3100142 [Sulfuriferula nivalis]
ATGACTACAAACGCCGTTGTTAGAGCTCGGATTGACGAGCATATCAAGGAAGAAGCATCAATCGTACTGGCTACGATGGG
TCTTACTGTATCAGATGCCTTCCGCATCATGCTCACGCGCATTGCGCGCGAGAAAGCTTTACCGTTTGATCCGCTAGTGC
CAAACGAAACCACGATAGCCGCCATGCGTGAGGCTCGGGCTGGTAACCTCAAAAGTTTTGATAGCGTTGATGCGCTGATG
GCTGATTTACATGCGGAAGATTGA