Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 499277..499882 Replicon chromosome
Accession NZ_AP021881
Organism Sulfuriferula nivalis strain SGTM

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag SFSGTM_RS02650 Protein ID WP_162083804.1
Coordinates 499586..499882 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag SFSGTM_RS02645 Protein ID WP_162083803.1
Coordinates 499277..499582 (-) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SFSGTM_RS02620 494729..496198 + 1470 WP_162083800.1 diguanylate cyclase -
SFSGTM_RS02625 496251..496556 + 306 WP_162083801.1 hypothetical protein -
SFSGTM_RS02630 496559..497425 + 867 WP_162086177.1 decaprenyl-phosphate phosphoribosyltransferase -
SFSGTM_RS02635 497422..498363 + 942 WP_162083802.1 flippase-like domain-containing protein -
SFSGTM_RS02640 498359..499258 + 900 WP_162086178.1 DMT family transporter -
SFSGTM_RS02645 499277..499582 - 306 WP_162083803.1 putative addiction module antidote protein Antitoxin
SFSGTM_RS02650 499586..499882 - 297 WP_162083804.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
SFSGTM_RS02655 500033..501898 - 1866 WP_162083805.1 molecular chaperone HtpG -
SFSGTM_RS02660 502041..503522 + 1482 WP_198420606.1 DUF1800 domain-containing protein -
SFSGTM_RS02665 503533..504753 + 1221 WP_162083807.1 DUF1501 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(14-93)

Antitoxin

Uncharacterized protein HI1420

(10-96)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11124.82 Da        Isoelectric Point: 9.9476

>T33488 WP_162083804.1 NZ_AP021881:c499882-499586 [Sulfuriferula nivalis]
MYIVKQHPEFSTWFGNLKDRVTRIRLGRRLDRVAQGNLGDVKSVGDGVFEMREFFGGGWRMYYIQRNDIIIVMLGGGDKS
TQATDIAKAIKLAATIEE

Download         Length: 297 bp

>T33488 NZ_AP021881:c499882-499586 [Sulfuriferula nivalis]
ATGTATATCGTCAAACAGCATCCCGAATTTAGTACATGGTTCGGCAACTTAAAAGACCGTGTAACACGTATTCGCCTTGG
TCGCAGACTGGATCGGGTAGCACAAGGTAATTTAGGCGACGTTAAATCTGTAGGTGACGGGGTCTTTGAAATGCGTGAAT
TTTTTGGTGGAGGTTGGCGCATGTATTATATTCAACGCAACGATATTATTATCGTGATGCTGGGTGGTGGCGACAAGTCC
ACTCAGGCAACAGATATTGCCAAAGCCATCAAACTTGCAGCAACTATCGAGGAGTAA

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 10847.43 Da        Isoelectric Point: 6.7178

>AT33488 WP_162083803.1 NZ_AP021881:c499582-499277 [Sulfuriferula nivalis]
MNKKTRIADLPEFDFTEHLKSEADIAAYLTIVLEEGDAAELAHALGVAARARGMSEIAAQSGLTREALYKALRSGAQPRF
DTINRVCGALGVRLVALPVHS

Download         Length: 306 bp

>AT33488 NZ_AP021881:c499582-499277 [Sulfuriferula nivalis]
ATGAACAAAAAAACTAGGATTGCCGACTTGCCAGAATTTGATTTTACTGAACATCTTAAAAGTGAAGCCGACATTGCCGC
TTATCTGACTATTGTGCTTGAAGAAGGCGATGCAGCAGAACTTGCACATGCACTTGGGGTCGCAGCACGCGCGCGCGGAA
TGAGTGAAATTGCCGCACAATCTGGCCTGACCCGCGAGGCATTGTACAAAGCATTACGATCAGGTGCACAGCCACGCTTT
GATACCATCAATCGTGTTTGCGGCGCATTAGGGGTGCGTTTGGTTGCGCTGCCTGTTCATTCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References