Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | mazEF/PRK09907-MazE |
Location | 217090..217667 | Replicon | chromosome |
Accession | NZ_AP021881 | ||
Organism | Sulfuriferula nivalis strain SGTM |
Toxin (Protein)
Gene name | mazF | Uniprot ID | - |
Locus tag | SFSGTM_RS01170 | Protein ID | WP_162083556.1 |
Coordinates | 217332..217667 (+) | Length | 112 a.a. |
Antitoxin (Protein)
Gene name | mazE | Uniprot ID | - |
Locus tag | SFSGTM_RS01165 | Protein ID | WP_162083555.1 |
Coordinates | 217090..217332 (+) | Length | 81 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
SFSGTM_RS01120 | 213162..214394 | - | 1233 | WP_162083547.1 | transposase | - |
SFSGTM_RS01125 | 214415..214831 | + | 417 | WP_162083548.1 | IS200/IS605 family transposase | - |
SFSGTM_RS01130 | 214806..215060 | + | 255 | WP_198420593.1 | BrnT family toxin | - |
SFSGTM_RS01135 | 215044..215310 | + | 267 | WP_162083550.1 | BrnA antitoxin family protein | - |
SFSGTM_RS01145 | 215603..215890 | + | 288 | WP_162083551.1 | CopG family transcriptional regulator | - |
SFSGTM_RS01150 | 215893..216183 | + | 291 | WP_162083552.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
SFSGTM_RS01155 | 216193..216543 | - | 351 | WP_162083553.1 | HigA family addiction module antidote protein | - |
SFSGTM_RS01160 | 216555..216836 | - | 282 | WP_162083554.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
SFSGTM_RS01165 | 217090..217332 | + | 243 | WP_162083555.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin |
SFSGTM_RS01170 | 217332..217667 | + | 336 | WP_162083556.1 | endoribonuclease MazF | Toxin |
SFSGTM_RS01175 | 217748..218149 | - | 402 | WP_162086150.1 | type II toxin-antitoxin system MqsA family antitoxin | - |
SFSGTM_RS01180 | 218152..218325 | - | 174 | WP_198420594.1 | type II toxin-antitoxin system MqsR family toxin | - |
SFSGTM_RS01185 | 218744..220288 | + | 1545 | WP_162083557.1 | plasmid recombination protein | - |
SFSGTM_RS01190 | 220356..221315 | - | 960 | WP_162083558.1 | acetyltransferase | - |
SFSGTM_RS01195 | 221366..222463 | - | 1098 | WP_162083559.1 | DUF1972 domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | flank | IS/Tn | - | - | 214463..214831 | 368 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 112 a.a. Molecular weight: 12048.93 Da Isoelectric Point: 8.4839
>T33485 WP_162083556.1 NZ_AP021881:217332-217667 [Sulfuriferula nivalis]
MGQSYVPESGDIVWLQFDPQAGHEQAGHRPAVVVSPASYNGKTGLMLCCLITTQIKGYPFEVVIAGDRSSAVLSDQIKSL
DWVARKATYKGKITPDELMIVRNKVSALIGK
MGQSYVPESGDIVWLQFDPQAGHEQAGHRPAVVVSPASYNGKTGLMLCCLITTQIKGYPFEVVIAGDRSSAVLSDQIKSL
DWVARKATYKGKITPDELMIVRNKVSALIGK
Download Length: 336 bp
>T33485 NZ_AP021881:217332-217667 [Sulfuriferula nivalis]
ATGGGGCAAAGCTATGTACCTGAATCAGGTGATATTGTGTGGTTACAATTCGATCCGCAGGCAGGGCATGAGCAAGCCGG
GCATAGGCCAGCGGTAGTTGTCAGTCCCGCATCCTACAATGGTAAAACCGGATTGATGTTGTGTTGCCTGATAACTACGC
AGATCAAAGGTTATCCATTCGAGGTTGTGATCGCTGGTGATCGATCAAGTGCCGTGTTGTCTGACCAGATAAAAAGTCTC
GATTGGGTTGCGCGCAAGGCTACTTATAAGGGAAAAATAACTCCCGATGAGTTAATGATAGTGCGAAATAAAGTATCTGC
CCTTATTGGCAAATAA
ATGGGGCAAAGCTATGTACCTGAATCAGGTGATATTGTGTGGTTACAATTCGATCCGCAGGCAGGGCATGAGCAAGCCGG
GCATAGGCCAGCGGTAGTTGTCAGTCCCGCATCCTACAATGGTAAAACCGGATTGATGTTGTGTTGCCTGATAACTACGC
AGATCAAAGGTTATCCATTCGAGGTTGTGATCGCTGGTGATCGATCAAGTGCCGTGTTGTCTGACCAGATAAAAAGTCTC
GATTGGGTTGCGCGCAAGGCTACTTATAAGGGAAAAATAACTCCCGATGAGTTAATGATAGTGCGAAATAAAGTATCTGC
CCTTATTGGCAAATAA
Antitoxin
Download Length: 81 a.a. Molecular weight: 8642.95 Da Isoelectric Point: 4.3466
>AT33485 WP_162083555.1 NZ_AP021881:217090-217332 [Sulfuriferula nivalis]
MRVIVKKWGNSAAVRIPAGIMESACLSLDASVDVREEGGRIIIEPIRSTEYDLAQLLADITPENLNIGADFGTPVGKEFL
MRVIVKKWGNSAAVRIPAGIMESACLSLDASVDVREEGGRIIIEPIRSTEYDLAQLLADITPENLNIGADFGTPVGKEFL
Download Length: 243 bp
>AT33485 NZ_AP021881:217090-217332 [Sulfuriferula nivalis]
ATGCGTGTAATCGTGAAGAAATGGGGAAACAGTGCTGCTGTTCGTATCCCTGCTGGAATAATGGAATCAGCTTGTTTGAG
TCTGGATGCGTCGGTTGATGTTCGGGAAGAAGGTGGCCGTATTATTATCGAGCCGATTCGGTCAACTGAATATGATCTGG
CGCAATTGCTTGCTGACATCACACCAGAAAATTTGAATATCGGCGCTGATTTTGGTACGCCAGTCGGCAAGGAGTTTTTG
TAA
ATGCGTGTAATCGTGAAGAAATGGGGAAACAGTGCTGCTGTTCGTATCCCTGCTGGAATAATGGAATCAGCTTGTTTGAG
TCTGGATGCGTCGGTTGATGTTCGGGAAGAAGGTGGCCGTATTATTATCGAGCCGATTCGGTCAACTGAATATGATCTGG
CGCAATTGCTTGCTGACATCACACCAGAAAATTTGAATATCGGCGCTGATTTTGGTACGCCAGTCGGCAAGGAGTTTTTG
TAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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