Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 199514..200178 Replicon chromosome
Accession NZ_AP021881
Organism Sulfuriferula nivalis strain SGTM

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag SFSGTM_RS01030 Protein ID WP_162083529.1
Coordinates 199750..200178 (+) Length 143 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag SFSGTM_RS01025 Protein ID WP_162083528.1
Coordinates 199514..199753 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SFSGTM_RS01005 195795..198302 - 2508 WP_162083526.1 tetratricopeptide repeat protein -
SFSGTM_RS01010 198439..198723 + 285 WP_162086148.1 BrnT family toxin -
SFSGTM_RS01015 198683..199048 + 366 WP_198420592.1 BrnA antitoxin family protein -
SFSGTM_RS01020 199139..199375 + 237 WP_162083527.1 type II toxin-antitoxin system prevent-host-death family antitoxin -
SFSGTM_RS01025 199514..199753 + 240 WP_162083528.1 Arc family DNA-binding protein Antitoxin
SFSGTM_RS01030 199750..200178 + 429 WP_162083529.1 type II toxin-antitoxin system VapC family toxin Toxin
SFSGTM_RS01035 200201..201058 - 858 WP_162083530.1 dTDP-4-dehydrorhamnose reductase -
SFSGTM_RS01040 201055..201597 - 543 WP_162083531.1 dTDP-4-dehydrorhamnose 3,5-epimerase -
SFSGTM_RS01045 201600..202484 - 885 WP_162083532.1 glucose-1-phosphate thymidylyltransferase RfbA -
SFSGTM_RS01050 202481..203545 - 1065 WP_162083533.1 dTDP-glucose 4,6-dehydratase -
SFSGTM_RS01055 203849..204115 + 267 WP_162083534.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
SFSGTM_RS01060 204255..204545 - 291 WP_162083535.1 helix-turn-helix domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-124)

Antitoxin

Arc-like DNA binding domain

(9-46)


Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 15198.42 Da        Isoelectric Point: 5.5882

>T33483 WP_162083529.1 NZ_AP021881:199750-200178 [Sulfuriferula nivalis]
MILLDTNIISEPLKAAGNANVLAWIDAQIIETLYLSTISLAELRFGIAALPEGKRRDTLHFSLEQRVLPLFVGRILSFDD
PASQSYATLRSSARAAGLAIAPADGYIAAIAATHGLAVATRDTSPFEAAGLTVINPWTWQAH

Download         Length: 429 bp

>T33483 NZ_AP021881:199750-200178 [Sulfuriferula nivalis]
ATGATCCTGCTCGATACCAACATCATTTCTGAACCATTGAAAGCGGCAGGCAACGCGAACGTACTTGCCTGGATAGACGC
ACAGATCATCGAAACGTTGTACCTCTCGACTATCAGTCTTGCGGAACTTCGCTTTGGGATCGCGGCGTTACCAGAGGGAA
AACGCCGCGATACGCTACATTTCAGTCTTGAGCAGCGTGTTTTACCGTTGTTTGTGGGGCGCATCCTATCGTTTGATGAT
CCTGCATCGCAATCCTATGCAACGCTACGCTCAAGCGCGCGTGCAGCTGGGTTGGCCATTGCGCCCGCAGATGGCTATAT
TGCGGCCATCGCGGCGACGCATGGTTTAGCGGTAGCTACGCGCGACACGTCGCCTTTTGAAGCTGCCGGCTTGACTGTCA
TCAACCCTTGGACGTGGCAGGCACATTGA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8753.97 Da        Isoelectric Point: 5.7255

>AT33483 WP_162083528.1 NZ_AP021881:199514-199753 [Sulfuriferula nivalis]
MASVTVRNLPDETHRALRVRAATHGRSTEAEIRAILECAVRPESRIKLGTLLAEIGREVGGIDLEIERDKTPSEPMSFE

Download         Length: 240 bp

>AT33483 NZ_AP021881:199514-199753 [Sulfuriferula nivalis]
ATGGCATCTGTCACCGTCCGCAACTTACCTGATGAAACGCACCGTGCGCTGCGTGTGCGTGCTGCTACGCATGGCCGCAG
CACTGAAGCTGAAATTCGGGCGATCCTCGAATGTGCTGTTCGACCTGAGAGTCGGATTAAGCTCGGCACCCTGCTAGCCG
AGATTGGCCGTGAAGTGGGCGGCATCGATCTTGAGATTGAACGCGATAAAACTCCGTCCGAACCAATGAGCTTTGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References