Detailed information of TA system TA033460

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relE-dinJ/YafQ-RelB
• Location: 6265771..6266303
• Replicon: chromosome
• Accession: NZ_AP021879
• Organism: Desulfosarcina ovata subsp. ovata strain oXyS1

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: GN112_RS27470
• Protein ID: WP_155313088.1
• Coordinates: 6265771..6266043 (-)
• Length: 91 a.a.

Antitoxin (Protein)

• Gene name: dinJ
• Uniprot ID: -
• Locus tag: GN112_RS27475
• Protein ID: WP_155313089.1
• Coordinates: 6266043..6266303 (-)
• Length: 87 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GN112_RS34080	6261981..6262466	+	486	Protein_5466	transposase	-
GN112_RS33880	6263077..6264384	+	1308	WP_155313086.1	PAS domain S-box protein	-
GN112_RS27460	6264488..6265264	-	777	WP_155313087.1	transposase	-
GN112_RS27465	6265477..6265665	+	189	WP_197743422.1	hypothetical protein	-
GN112_RS27470	6265771..6266043	-	273	WP_155313088.1	type II toxin-antitoxin system YafQ family toxin	Toxin
GN112_RS27475	6266043..6266303	-	261	WP_155313089.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
GN112_RS27480	6266622..6267254	-	633	WP_155313090.1	PqiC family protein	-
GN112_RS27485	6267259..6268296	-	1038	WP_155313091.1	MCE family protein	-
GN112_RS27490	6268393..6269541	-	1149	WP_155313092.1	ABC transporter permease	-
GN112_RS27495	6269538..6270311	-	774	WP_155313093.1	ATP-binding cassette domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	6260101..6288196	28095

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, YafQ-like toxin (4-89)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (5-84)

Sequences

Toxin

Protein

• Length: 91 a.a.
• Molecular weight: 10852.61 Da
• Isoelectric Point: 10.0067

>T33460 WP_155313088.1 NZ_AP021879:c6266043-6265771 [Desulfosarcina ovata subsp. ovata]
MLTPVYTRQFERDTKRMKKRGKNLDKLKIIIRSIVSEEPLDAIHRDHKLIGNWKGRRECHIETDWLLIYMVESDRVVFER
TGTHSDLFQL

Nucleotide

• Length: 273 bp

>T33460 NZ_AP021879:c6266043-6265771 [Desulfosarcina ovata subsp. ovata]
ATGCTCACCCCTGTATATACCAGACAGTTTGAGCGGGATACCAAGCGGATGAAAAAGCGAGGGAAAAACCTTGATAAGCT
GAAGATAATCATCAGATCTATAGTCTCGGAAGAACCACTTGACGCGATTCATCGGGACCATAAGCTAATTGGCAATTGGA
AGGGGCGACGGGAATGCCATATAGAAACGGATTGGCTGTTGATCTACATGGTTGAATCCGATCGCGTTGTATTCGAGCGA
ACCGGAACACACTCAGATTTATTCCAATTATAA

Antitoxin

Protein

• Length: 87 a.a.
• Molecular weight: 9645.21 Da
• Isoelectric Point: 9.0424

>AT33460 WP_155313089.1 NZ_AP021879:c6266303-6266043 [Desulfosarcina ovata subsp. ovata]
MGKTSTIRARIEPDLKGKAEHIFKQLGLTTTQAITLFYKQVELKKGLPFDVAIPNEITRKTFSDTDAGRDLIICSDTDDM
FKKLGI

Nucleotide

• Length: 261 bp

>AT33460 NZ_AP021879:c6266303-6266043 [Desulfosarcina ovata subsp. ovata]
ATGGGAAAAACTTCCACTATCAGAGCTCGGATTGAACCAGACTTAAAGGGTAAAGCTGAGCACATATTTAAGCAGCTTGG
ACTAACCACAACCCAGGCAATTACCTTGTTTTATAAGCAGGTTGAACTTAAAAAAGGGCTGCCTTTCGACGTAGCTATTC
CAAACGAAATTACACGTAAGACGTTTTCCGATACAGATGCCGGACGTGACCTGATCATTTGCAGCGACACTGACGATATG
TTCAAAAAGTTGGGCATCTGA