Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 3914144..3914688 Replicon chromosome
Accession NZ_AP021879
Organism Desulfosarcina ovata subsp. ovata strain oXyS1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag GN112_RS17335 Protein ID WP_155311368.1
Coordinates 3914144..3914419 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag GN112_RS17340 Protein ID WP_155311369.1
Coordinates 3914419..3914688 (-) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GN112_RS17305 3909840..3910445 - 606 WP_155311363.1 RlmE family RNA methyltransferase -
GN112_RS17310 3910548..3911912 - 1365 WP_155311364.1 DNA repair protein RadA -
GN112_RS17315 3912251..3912571 + 321 WP_155311365.1 hypothetical protein -
GN112_RS17320 3912577..3913470 + 894 WP_155311366.1 lytic murein transglycosylase -
GN112_RS17325 3913477..3913695 + 219 WP_155311367.1 PLD nuclease N-terminal domain-containing protein -
GN112_RS17335 3914144..3914419 - 276 WP_155311368.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GN112_RS17340 3914419..3914688 - 270 WP_155311369.1 ribbon-helix-helix domain-containing protein Antitoxin
GN112_RS17345 3914861..3915145 - 285 WP_155311370.1 hypothetical protein -
GN112_RS17350 3915362..3915874 + 513 WP_155311371.1 hypothetical protein -
GN112_RS17355 3915853..3916320 + 468 WP_155311372.1 PAS domain S-box protein -
GN112_RS33620 3916392..3917195 + 804 WP_162458981.1 sigma 54-interacting transcriptional regulator -
GN112_RS33860 3917279..3917959 + 681 WP_176603543.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(9-46)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10867.70 Da        Isoelectric Point: 10.4248

>T33453 WP_155311368.1 NZ_AP021879:c3914419-3914144 [Desulfosarcina ovata subsp. ovata]
MELRWTSKALSDLVRLYEFLAPVNKPAAARAIQALTKAPTILLTNPRIGERLFQFEPREVRRILVKNYEVRYEIQDSIIY
VLRLWHTREDR

Download         Length: 276 bp

>T33453 NZ_AP021879:c3914419-3914144 [Desulfosarcina ovata subsp. ovata]
ATGGAGTTGAGGTGGACCAGCAAGGCGCTTTCCGACTTGGTGCGGTTGTATGAATTCCTGGCTCCGGTGAATAAGCCGGC
CGCCGCGAGGGCGATTCAGGCACTGACCAAAGCCCCAACCATCTTGCTGACCAATCCGCGCATTGGTGAGCGACTTTTCC
AGTTCGAGCCGCGCGAGGTACGGAGGATTCTGGTCAAGAACTACGAAGTCCGCTATGAGATTCAGGATTCGATTATCTAC
GTGCTGAGACTTTGGCATACCCGAGAGGACCGCTGA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9885.17 Da        Isoelectric Point: 4.5560

>AT33453 WP_155311369.1 NZ_AP021879:c3914688-3914419 [Desulfosarcina ovata subsp. ovata]
MTQAATKVLTAHVPLQLVDKVDQMAARLERSRAWIIKQALSAWIAQEEERDRLTQEALADVDAGSVIDHQAVQAWADSLD
SDQPLPVPR

Download         Length: 270 bp

>AT33453 NZ_AP021879:c3914688-3914419 [Desulfosarcina ovata subsp. ovata]
ATGACACAAGCAGCAACTAAAGTGCTGACCGCACATGTGCCGCTTCAGCTGGTCGACAAGGTCGATCAGATGGCTGCACG
GCTTGAACGCTCAAGAGCCTGGATCATAAAACAGGCGCTTTCCGCCTGGATAGCCCAGGAGGAGGAGCGCGACCGCCTGA
CCCAAGAGGCGCTGGCAGACGTGGACGCCGGCAGCGTCATCGACCACCAGGCCGTGCAGGCGTGGGCTGACAGTCTTGAC
TCCGACCAGCCGCTGCCGGTACCACGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References