Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/Txe-YefM
Location 3293969..3294471 Replicon chromosome
Accession NZ_AP021879
Organism Desulfosarcina ovata subsp. ovata strain oXyS1

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag GN112_RS14555 Protein ID WP_155310878.1
Coordinates 3294205..3294471 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag GN112_RS14550 Protein ID WP_083456022.1
Coordinates 3293969..3294211 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GN112_RS14530 3290003..3290617 - 615 WP_155310875.1 hypothetical protein -
GN112_RS14535 3291087..3292418 - 1332 WP_155308529.1 transposase -
GN112_RS14540 3292632..3292928 - 297 WP_155310876.1 hypothetical protein -
GN112_RS14545 3292990..3293694 - 705 WP_155310877.1 hypothetical protein -
GN112_RS14550 3293969..3294211 + 243 WP_083456022.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
GN112_RS14555 3294205..3294471 + 267 WP_155310878.1 Txe/YoeB family addiction module toxin Toxin
GN112_RS14560 3294642..3295016 + 375 WP_155310879.1 hypothetical protein -
GN112_RS14565 3295407..3295994 + 588 WP_155310880.1 nucleotidyltransferase domain-containing protein -
GN112_RS14570 3296252..3296788 - 537 WP_155310881.1 pyridoxal phosphate-dependent aminotransferase -
GN112_RS14575 3296989..3297282 + 294 WP_155310882.1 hypothetical protein -
GN112_RS14580 3297458..3298204 + 747 WP_155310883.1 class I SAM-dependent methyltransferase -
GN112_RS14585 3298204..3298584 + 381 WP_155310884.1 HigA family addiction module antidote protein -
GN112_RS14590 3298909..3299136 + 228 WP_155310885.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-69)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10389.07 Da        Isoelectric Point: 9.9940

>T33452 WP_155310878.1 NZ_AP021879:3294205-3294471 [Desulfosarcina ovata subsp. ovata]
MVNYKVVFTKQAQKDAKKLSASGFKTKAENIIEILRENPYQTPPFYEKLVGDLAGAYSRRINIQHRLVYEVIEDQKIVKV
IRMWTHYE

Download         Length: 267 bp

>T33452 NZ_AP021879:3294205-3294471 [Desulfosarcina ovata subsp. ovata]
TTGGTAAATTACAAGGTCGTTTTTACAAAACAAGCACAAAAAGACGCGAAAAAATTATCCGCCTCCGGTTTCAAGACAAA
GGCCGAAAATATTATCGAAATATTGCGGGAAAATCCTTATCAGACCCCTCCTTTCTATGAAAAACTTGTAGGCGATTTAG
CTGGCGCATATTCCCGTCGTATAAATATTCAACACCGACTGGTCTATGAGGTTATCGAAGACCAAAAGATTGTAAAAGTT
ATCCGTATGTGGACACATTATGAATAG

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9117.39 Da        Isoelectric Point: 4.4488

>AT33452 WP_083456022.1 NZ_AP021879:3293969-3294211 [Desulfosarcina ovata subsp. ovata]
MPTLSATEARSKLYRLIDQTALSHEPIVITSKRGNAVLLSEDDWRAIQETMYLLNIPGMRESIREGLATPVEDCKEELDW

Download         Length: 243 bp

>AT33452 NZ_AP021879:3293969-3294211 [Desulfosarcina ovata subsp. ovata]
ATGCCGACTTTATCAGCCACTGAGGCAAGATCGAAACTTTACCGTCTTATCGACCAAACCGCCTTGTCCCATGAACCAAT
TGTAATTACAAGTAAAAGAGGCAATGCTGTTCTTCTATCCGAGGACGATTGGCGGGCAATCCAAGAAACAATGTACCTGT
TAAACATCCCAGGCATGCGCGAGTCAATTCGTGAAGGTTTGGCAACACCTGTTGAGGATTGCAAAGAGGAACTCGATTGG
TAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References