Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 6748497..6749140 Replicon chromosome
Accession NZ_AP021876
Organism Desulfosarcina ovata subsp. sediminis strain 28bB2T

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag GN113_RS29285 Protein ID WP_173179913.1
Coordinates 6748497..6748892 (-) Length 132 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag GN113_RS29290 Protein ID WP_173179914.1
Coordinates 6748889..6749140 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GN113_RS29260 6744265..6745656 + 1392 WP_155324974.1 MFS transporter -
GN113_RS29265 6745811..6747106 + 1296 WP_155324975.1 acetyl-CoA hydrolase/transferase family protein -
GN113_RS29270 6747276..6747731 + 456 WP_155324976.1 creatininase family protein -
GN113_RS29280 6747942..6748286 + 345 WP_155324978.1 chromate resistance protein -
GN113_RS29285 6748497..6748892 - 396 WP_173179913.1 type II toxin-antitoxin system VapC family toxin Toxin
GN113_RS29290 6748889..6749140 - 252 WP_173179914.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
GN113_RS29295 6749239..6750084 + 846 WP_173179916.1 creatininase family protein -
GN113_RS29300 6750091..6751062 - 972 WP_155324981.1 xanthine dehydrogenase family protein subunit M -
GN113_RS29305 6751059..6753341 - 2283 WP_155324982.1 xanthine dehydrogenase family protein molybdopterin-binding subunit -
GN113_RS29310 6753334..6753864 - 531 WP_155324983.1 (2Fe-2S)-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-126)

Antitoxin

Antitoxin VapB-like

(1-83)


Sequences

Toxin        


Download         Length: 132 a.a.        Molecular weight: 14657.01 Da        Isoelectric Point: 6.7183

>T33437 WP_173179913.1 NZ_AP021876:c6748892-6748497 [Desulfosarcina ovata subsp. sediminis]
MKIVADTSAFIAILQKEQDADIYRQTLMEAEKILVSTATAVELHIVVTSRLGAEGILRFNHLLAQPLFEIMPVDVQQMAL
ANQAYERFGKGRHPARLNYGDLFSYALAKSRNLPLLFKGDDFSKTDLVSCL

Download         Length: 396 bp

>T33437 NZ_AP021876:c6748892-6748497 [Desulfosarcina ovata subsp. sediminis]
ATGAAAATCGTTGCCGACACATCTGCATTCATTGCGATCTTACAAAAAGAGCAAGATGCCGACATTTATCGGCAAACCTT
AATGGAAGCTGAAAAAATTCTGGTTAGTACGGCCACGGCAGTAGAGTTACACATTGTCGTCACCTCAAGACTGGGTGCGG
AAGGTATTTTACGTTTTAACCATTTGTTGGCCCAACCCCTTTTTGAAATTATGCCAGTGGATGTTCAACAAATGGCTCTC
GCCAACCAGGCCTATGAACGCTTCGGCAAGGGAAGACATCCGGCAAGACTCAATTATGGAGACCTGTTTTCCTATGCGCT
GGCGAAAAGCCGGAATTTGCCTTTGTTATTCAAAGGTGACGACTTTTCAAAAACCGATCTCGTATCCTGCCTTTAG

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9255.52 Da        Isoelectric Point: 6.7265

>AT33437 WP_173179914.1 NZ_AP021876:c6749140-6748889 [Desulfosarcina ovata subsp. sediminis]
MALNIANRKVEKKAIQASRILGVNKTAAVEIALDYYLEHHGSKEKESTTRREAARLLDELAALPVLDHRKSDDILGYDEN
GLP

Download         Length: 252 bp

>AT33437 NZ_AP021876:c6749140-6748889 [Desulfosarcina ovata subsp. sediminis]
ATGGCCCTTAATATTGCAAACCGTAAAGTCGAAAAAAAAGCAATTCAAGCTAGCCGCATCTTGGGCGTCAATAAGACCGC
GGCAGTCGAAATTGCGCTTGATTACTATTTGGAACATCATGGTTCCAAGGAAAAAGAGAGCACGACCCGCCGGGAAGCGG
CCCGTTTGCTTGATGAACTGGCGGCACTTCCCGTTCTGGACCATCGAAAATCGGACGACATTCTCGGTTACGATGAAAAT
GGTTTGCCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References