Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/Txe-YefM
Location 4489733..4490235 Replicon chromosome
Accession NZ_AP021876
Organism Desulfosarcina ovata subsp. sediminis strain 28bB2T

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag GN113_RS19570 Protein ID WP_155323611.1
Coordinates 4489969..4490235 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag GN113_RS19565 Protein ID WP_083456022.1
Coordinates 4489733..4489975 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GN113_RS19545 4485090..4485905 - 816 WP_155320765.1 AAA family ATPase -
GN113_RS19550 4485902..4487287 - 1386 WP_173178975.1 DDE-type integrase/transposase/recombinase -
GN113_RS19555 4487381..4488178 - 798 WP_155320767.1 hypothetical protein -
GN113_RS19560 4488754..4489458 - 705 WP_155323610.1 hypothetical protein -
GN113_RS19565 4489733..4489975 + 243 WP_083456022.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
GN113_RS19570 4489969..4490235 + 267 WP_155323611.1 Txe/YoeB family addiction module toxin Toxin
GN113_RS19575 4490406..4490780 + 375 WP_155323612.1 hypothetical protein -
GN113_RS19580 4491171..4491758 + 588 WP_155310880.1 nucleotidyltransferase domain-containing protein -
GN113_RS19585 4492015..4492550 - 536 Protein_3903 pyridoxal phosphate-dependent aminotransferase -
GN113_RS19590 4492751..4493044 + 294 WP_155323613.1 hypothetical protein -
GN113_RS19595 4493220..4493966 + 747 WP_155323614.1 class I SAM-dependent methyltransferase -
GN113_RS19600 4494191..4494406 + 216 WP_155323615.1 HigA family addiction module antidote protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(26-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-69)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10385.08 Da        Isoelectric Point: 9.9940

>T33432 WP_155323611.1 NZ_AP021876:4489969-4490235 [Desulfosarcina ovata subsp. sediminis]
MVNYKVVFTKQAQKDAKKLSASGFKTKAENIIEILRENPYQPPPFYEKLVGDLAGAYSRRINIQHRLVYEVIEDQKIVKV
IRMWTHYE

Download         Length: 267 bp

>T33432 NZ_AP021876:4489969-4490235 [Desulfosarcina ovata subsp. sediminis]
TTGGTAAATTACAAGGTCGTTTTTACAAAACAAGCACAAAAAGACGCGAAAAAATTATCCGCCTCCGGTTTCAAGACAAA
GGCCGAAAATATTATCGAAATATTGCGGGAAAATCCTTATCAGCCCCCTCCTTTCTATGAAAAACTTGTAGGCGATTTAG
CTGGCGCATATTCCCGTCGTATAAATATTCAACACCGACTGGTCTATGAGGTTATCGAAGACCAAAAGATTGTAAAAGTT
ATCCGTATGTGGACACATTATGAATAG

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9117.39 Da        Isoelectric Point: 4.4488

>AT33432 WP_083456022.1 NZ_AP021876:4489733-4489975 [Desulfosarcina ovata subsp. sediminis]
MPTLSATEARSKLYRLIDQTALSHEPIVITSKRGNAVLLSEDDWRAIQETMYLLNIPGMRESIREGLATPVEDCKEELDW

Download         Length: 243 bp

>AT33432 NZ_AP021876:4489733-4489975 [Desulfosarcina ovata subsp. sediminis]
ATGCCGACTTTATCAGCCACTGAGGCAAGATCGAAACTTTACCGTCTTATCGACCAAACCGCCTTGTCCCATGAACCAAT
TGTAATTACAAGTAAAAGAGGCAATGCTGTTCTTCTATCCGAGGACGATTGGCGGGCAATCCAAGAAACAATGTACCTGT
TAAACATCCCAGGCATGCGCGAGTCAATTCGTGAAGGTTTGGCAACACCTGTTGAGGATTGCAAAGAGGAACTCGATTGG
TAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References