Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-dinJ/YafQ-RelB
Location 3692941..3693473 Replicon chromosome
Accession NZ_AP021876
Organism Desulfosarcina ovata subsp. sediminis strain 28bB2T

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag GN113_RS16305 Protein ID WP_155313088.1
Coordinates 3693201..3693473 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID -
Locus tag GN113_RS16300 Protein ID WP_155313089.1
Coordinates 3692941..3693201 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GN113_RS16280 3688792..3689589 - 798 WP_155320767.1 hypothetical protein -
GN113_RS16285 3689907..3690851 + 945 WP_155323085.1 ABC transporter permease -
GN113_RS16290 3690948..3691985 + 1038 WP_155323086.1 MCE family protein -
GN113_RS16295 3691990..3692622 + 633 WP_155323087.1 PqiC family protein -
GN113_RS16300 3692941..3693201 + 261 WP_155313089.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
GN113_RS16305 3693201..3693473 + 273 WP_155313088.1 type II toxin-antitoxin system YafQ family toxin Toxin
GN113_RS16310 3693579..3693767 - 189 WP_197743422.1 hypothetical protein -
GN113_RS37275 3694299..3694865 - 567 Protein_3246 transposase -
GN113_RS16320 3696409..3697455 - 1047 WP_155323088.1 spermidine/putrescine ABC transporter substrate-binding protein -
GN113_RS16325 3697513..3698313 - 801 WP_155323089.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(4-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-84)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10852.61 Da        Isoelectric Point: 10.0067

>T33429 WP_155313088.1 NZ_AP021876:3693201-3693473 [Desulfosarcina ovata subsp. sediminis]
MLTPVYTRQFERDTKRMKKRGKNLDKLKIIIRSIVSEEPLDAIHRDHKLIGNWKGRRECHIETDWLLIYMVESDRVVFER
TGTHSDLFQL

Download         Length: 273 bp

>T33429 NZ_AP021876:3693201-3693473 [Desulfosarcina ovata subsp. sediminis]
ATGCTCACCCCTGTATATACCAGACAGTTTGAGCGGGATACCAAGCGGATGAAAAAGCGAGGGAAAAACCTTGATAAGCT
GAAGATAATCATCAGATCTATAGTCTCGGAAGAACCACTTGACGCGATTCATCGGGACCATAAGCTAATTGGCAATTGGA
AGGGGCGACGGGAATGCCATATAGAAACGGATTGGCTGTTGATCTACATGGTTGAATCCGATCGCGTTGTATTCGAGCGA
ACCGGAACACACTCAGATTTATTCCAATTATAA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9645.21 Da        Isoelectric Point: 9.0424

>AT33429 WP_155313089.1 NZ_AP021876:3692941-3693201 [Desulfosarcina ovata subsp. sediminis]
MGKTSTIRARIEPDLKGKAEHIFKQLGLTTTQAITLFYKQVELKKGLPFDVAIPNEITRKTFSDTDAGRDLIICSDTDDM
FKKLGI

Download         Length: 261 bp

>AT33429 NZ_AP021876:3692941-3693201 [Desulfosarcina ovata subsp. sediminis]
ATGGGAAAAACTTCCACTATCAGAGCTCGGATTGAACCAGACTTAAAGGGTAAAGCTGAGCACATATTTAAGCAGCTTGG
ACTAACCACAACCCAGGCAATTACCTTGTTTTATAAGCAGGTTGAACTTAAAAAAGGGCTGCCTTTCGACGTAGCTATTC
CAAACGAAATTACACGTAAGACGTTTTCCGATACAGATGCCGGACGTGACCTGATCATTTGCAGCGACACTGACGATATG
TTCAAAAAGTTGGGCATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References