Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | VII | Classification (family/domain) | HepT-MntA/HepT(toxin) |
Location | 909321..910033 | Replicon | chromosome |
Accession | NZ_AP021876 | ||
Organism | Desulfosarcina ovata subsp. sediminis strain 28bB2T |
Toxin (Protein)
Gene name | hepT | Uniprot ID | - |
Locus tag | GN113_RS04230 | Protein ID | WP_197910407.1 |
Coordinates | 909321..909581 (-) | Length | 87 a.a. |
Antitoxin (Protein)
Gene name | mntA | Uniprot ID | - |
Locus tag | GN113_RS04235 | Protein ID | WP_155309100.1 |
Coordinates | 909608..910033 (-) | Length | 142 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
GN113_RS04195 | 905071..906198 | - | 1128 | Protein_831 | putative DNA binding domain-containing protein | - |
GN113_RS04200 | 906474..906896 | - | 423 | WP_155321291.1 | nucleotidyltransferase domain-containing protein | - |
GN113_RS04205 | 906908..907327 | - | 420 | WP_155309094.1 | DUF86 domain-containing protein | - |
GN113_RS04210 | 907324..907746 | - | 423 | WP_155321292.1 | hypothetical protein | - |
GN113_RS04215 | 907913..908212 | - | 300 | WP_155321293.1 | DUF86 domain-containing protein | - |
GN113_RS04220 | 908422..908922 | - | 501 | WP_155309097.1 | GNAT family N-acetyltransferase | - |
GN113_RS04225 | 908919..909206 | - | 288 | WP_155309098.1 | DUF1778 domain-containing protein | - |
GN113_RS04230 | 909321..909581 | - | 261 | WP_197910407.1 | DUF86 domain-containing protein | Toxin |
GN113_RS04235 | 909608..910033 | - | 426 | WP_155309100.1 | nucleotidyltransferase domain-containing protein | Antitoxin |
GN113_RS04240 | 910182..910487 | - | 306 | WP_155314130.1 | nucleotidyltransferase domain-containing protein | - |
GN113_RS04245 | 910493..910930 | - | 438 | WP_155309101.1 | nucleotidyltransferase substrate binding protein | - |
GN113_RS04250 | 910927..911214 | - | 288 | WP_155309102.1 | hypothetical protein | - |
GN113_RS04255 | 911510..912376 | - | 867 | WP_155321294.1 | dTDP-4-dehydrorhamnose reductase | - |
GN113_RS04260 | 912592..912840 | + | 249 | WP_155309104.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | - |
GN113_RS04265 | 912841..913176 | + | 336 | WP_155321295.1 | type II toxin-antitoxin system PemK/MazF family toxin | - |
GN113_RS04270 | 913288..913848 | - | 561 | WP_155321296.1 | dTDP-4-dehydrorhamnose 3,5-epimerase | - |
GN113_RS04275 | 913862..914260 | - | 399 | WP_155309107.1 | type II toxin-antitoxin system VapC family toxin | - |
GN113_RS04280 | 914290..914520 | - | 231 | WP_155309108.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 87 a.a. Molecular weight: 9818.47 Da Isoelectric Point: 9.9383
>T33418 WP_197910407.1 NZ_AP021876:c909581-909321 [Desulfosarcina ovata subsp. sediminis]
MSGACHLVRVRKLGVPQESRDAFDMLGEADLLKPVLRDRLKSMVGFRNVAVHGYRKLNIEIVRTIVETRLGDFREFAKVV
LQEGHE
MSGACHLVRVRKLGVPQESRDAFDMLGEADLLKPVLRDRLKSMVGFRNVAVHGYRKLNIEIVRTIVETRLGDFREFAKVV
LQEGHE
Download Length: 261 bp
>T33418 NZ_AP021876:c909581-909321 [Desulfosarcina ovata subsp. sediminis]
TTGAGCGGTGCCTGTCATCTCGTCCGGGTGCGTAAATTGGGGGTGCCGCAGGAATCCAGAGACGCTTTCGATATGCTTGG
CGAAGCTGACCTGTTGAAACCGGTATTGCGTGATCGCCTCAAGTCGATGGTCGGATTCCGCAATGTTGCTGTACACGGCT
ATCGCAAACTGAACATTGAAATTGTTCGTACCATTGTTGAAACACGCCTTGGTGATTTCCGCGAGTTCGCCAAAGTGGTA
TTGCAGGAAGGGCATGAGTGA
TTGAGCGGTGCCTGTCATCTCGTCCGGGTGCGTAAATTGGGGGTGCCGCAGGAATCCAGAGACGCTTTCGATATGCTTGG
CGAAGCTGACCTGTTGAAACCGGTATTGCGTGATCGCCTCAAGTCGATGGTCGGATTCCGCAATGTTGCTGTACACGGCT
ATCGCAAACTGAACATTGAAATTGTTCGTACCATTGTTGAAACACGCCTTGGTGATTTCCGCGAGTTCGCCAAAGTGGTA
TTGCAGGAAGGGCATGAGTGA
Antitoxin
Download Length: 142 a.a. Molecular weight: 15725.85 Da Isoelectric Point: 4.7851
>AT33418 WP_155309100.1 NZ_AP021876:c910033-909608 [Desulfosarcina ovata subsp. sediminis]
MSLNVLLNSQLQKELIEEICSTVHSCVAIYRFGSWGTAAQRKGSDIDIAVLAASPLDPVGRWDLAQKLASIAGRDVDLVD
LLRASTVLRMQVVAYGERLHCVDAEAAERFEDNVFSSYAKLNEERRLILEDVNRRGSVYDQ
MSLNVLLNSQLQKELIEEICSTVHSCVAIYRFGSWGTAAQRKGSDIDIAVLAASPLDPVGRWDLAQKLASIAGRDVDLVD
LLRASTVLRMQVVAYGERLHCVDAEAAERFEDNVFSSYAKLNEERRLILEDVNRRGSVYDQ
Download Length: 426 bp
>AT33418 NZ_AP021876:c910033-909608 [Desulfosarcina ovata subsp. sediminis]
ATGTCGCTGAATGTGTTGTTGAATTCACAATTGCAGAAGGAACTTATTGAAGAGATCTGCTCCACTGTCCACAGTTGTGT
GGCGATTTATCGCTTTGGCTCATGGGGCACGGCTGCTCAGAGAAAAGGGAGCGATATAGACATTGCCGTCTTGGCTGCAT
CGCCGCTTGATCCGGTTGGTCGTTGGGATCTTGCCCAGAAATTGGCATCAATAGCTGGTCGGGATGTTGACCTGGTCGAT
TTGCTGAGGGCTTCAACGGTTTTACGTATGCAGGTGGTGGCGTATGGTGAGCGGCTTCATTGTGTTGATGCCGAAGCGGC
TGAACGTTTTGAAGATAACGTATTTTCCAGCTATGCCAAGCTCAATGAGGAGCGCCGCTTGATTCTTGAGGATGTGAATA
GGCGAGGGAGTGTGTATGACCAGTGA
ATGTCGCTGAATGTGTTGTTGAATTCACAATTGCAGAAGGAACTTATTGAAGAGATCTGCTCCACTGTCCACAGTTGTGT
GGCGATTTATCGCTTTGGCTCATGGGGCACGGCTGCTCAGAGAAAAGGGAGCGATATAGACATTGCCGTCTTGGCTGCAT
CGCCGCTTGATCCGGTTGGTCGTTGGGATCTTGCCCAGAAATTGGCATCAATAGCTGGTCGGGATGTTGACCTGGTCGAT
TTGCTGAGGGCTTCAACGGTTTTACGTATGCAGGTGGTGGCGTATGGTGAGCGGCTTCATTGTGTTGATGCCGAAGCGGC
TGAACGTTTTGAAGATAACGTATTTTCCAGCTATGCCAAGCTCAATGAGGAGCGCCGCTTGATTCTTGAGGATGTGAATA
GGCGAGGGAGTGTGTATGACCAGTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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