Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-RelB
Location 467837..468353 Replicon chromosome
Accession NZ_AP021870
Organism Vibrio gangliei strain DSM 104291

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag Vgang_RS14120 Protein ID WP_105901486.1
Coordinates 468084..468353 (+) Length 90 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag Vgang_RS14115 Protein ID WP_105901485.1
Coordinates 467837..468091 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Vgang_RS14090 463278..465383 + 2106 WP_105901482.1 phytase -
Vgang_RS14095 465534..466079 + 546 WP_105901801.1 lipocalin family protein -
Vgang_RS14100 466287..466661 + 375 WP_105901483.1 MazG nucleotide pyrophosphohydrolase domain-containing protein -
Vgang_RS14105 466785..467561 + 777 WP_105901484.1 aminoglycoside phosphotransferase family protein -
Vgang_RS14110 467590..467724 - 135 Protein_420 GNAT family N-acetyltransferase -
Vgang_RS14115 467837..468091 + 255 WP_105901485.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
Vgang_RS14120 468084..468353 + 270 WP_105901486.1 Txe/YoeB family addiction module toxin Toxin
Vgang_RS14125 468469..469869 - 1401 WP_105901487.1 ATP-dependent RNA helicase DbpA -
Vgang_RS14130 469888..470115 - 228 WP_105901488.1 glutaredoxin family protein -
Vgang_RS14135 470159..470728 - 570 WP_105901489.1 DUF1415 domain-containing protein -
Vgang_RS14140 470838..471359 + 522 WP_105901490.1 DUF2058 domain-containing protein -
Vgang_RS14145 471439..472041 - 603 WP_105901491.1 TetR/AcrR family transcriptional regulator -
Vgang_RS14150 472192..472803 + 612 WP_105901492.1 glutathione S-transferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(10-89)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10656.05 Da        Isoelectric Point: 8.8497

>T33391 WP_105901486.1 NZ_AP021870:468084-468353 [Vibrio gangliei]
MSNSKRLLSWTDDAWDDYLYWQTQDKKTLKRINKLINDVKRSPFEGIGKPEPLKENLSGFWSRRIDDTNRLVYAVDEQAI
TIISCRYHY

Download         Length: 270 bp

>T33391 NZ_AP021870:468084-468353 [Vibrio gangliei]
ATGAGTAATAGCAAGCGGTTATTGTCTTGGACTGATGACGCTTGGGATGACTACCTATATTGGCAAACTCAAGATAAGAA
AACACTCAAGCGTATCAACAAACTCATCAATGATGTTAAGCGCTCTCCATTTGAAGGCATCGGTAAACCAGAGCCGTTAA
AAGAGAACTTATCTGGTTTTTGGTCTCGTCGTATTGATGACACAAATAGGCTTGTTTACGCAGTAGATGAACAAGCGATA
ACAATAATCTCATGTCGTTACCACTACTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9527.68 Da        Isoelectric Point: 5.0623

>AT33391 WP_105901485.1 NZ_AP021870:467837-468091 [Vibrio gangliei]
MRIVSFTEARNSLKAVLDGVVNDADTTVITRRDSEDVVVMSLDYYNSLMETVHLLRSPQNAEHLNRSISQYRAGKTTARE
LIDE

Download         Length: 255 bp

>AT33391 NZ_AP021870:467837-468091 [Vibrio gangliei]
ATGAGAATCGTATCTTTTACTGAAGCACGGAATAGTTTAAAAGCGGTTTTAGATGGTGTTGTGAATGATGCAGACACAAC
GGTAATTACTCGTCGTGATTCGGAAGATGTTGTTGTAATGTCTTTAGATTATTACAATAGCTTAATGGAGACAGTTCACT
TACTTCGTTCTCCTCAAAATGCAGAGCACCTAAATCGTTCAATATCGCAGTATCGTGCAGGTAAAACGACAGCACGAGAA
TTAATCGATGAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References