33390

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 1805011..1805519 Replicon chromosome
Accession NZ_AP021869
Organism Vibrio gangliei strain DSM 104291

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag Vgang_RS08245 Protein ID WP_105903755.1
Coordinates 1805011..1805271 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag Vgang_RS08250 Protein ID WP_105903754.1
Coordinates 1805268..1805519 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Vgang_RS08215 1800284..1800802 - 519 WP_105903323.1 RNA methyltransferase -
Vgang_RS08220 1800873..1802048 - 1176 WP_105903324.1 multidrug effflux MFS transporter -
Vgang_RS08225 1802179..1802670 + 492 WP_157946044.1 MarR family transcriptional regulator -
Vgang_RS08235 1803192..1803773 + 582 WP_105903757.1 DNA endonuclease SmrA -
Vgang_RS08240 1803920..1804996 + 1077 WP_105903756.1 23S rRNA pseudouridine(2604) synthase RluF -
Vgang_RS08245 1805011..1805271 - 261 WP_105903755.1 Txe/YoeB family addiction module toxin Toxin
Vgang_RS08250 1805268..1805519 - 252 WP_105903754.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
Vgang_RS08255 1805603..1806715 - 1113 WP_105903753.1 ABC transporter permease -
Vgang_RS08260 1806712..1807656 - 945 WP_105903752.1 ABC transporter ATP-binding protein -
Vgang_RS08265 1807656..1808612 - 957 WP_105903751.1 HlyD family efflux transporter periplasmic adaptor subunit -
Vgang_RS08270 1808729..1809391 + 663 WP_105903750.1 CerR family C-terminal domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10420.89 Da        Isoelectric Point: 9.8040

>T33390 WP_105903755.1 NZ_AP021869:c1805271-1805011 [Vibrio gangliei]
MKLTFSSHAWEDYLYWQSTDKKVLKRINLLIKDIQREPYDGIGKPEPLKHGLSGYWSRRINDEHRIVYRYHDNTILIAQL
RFHYGS

Download         Length: 261 bp

>T33390 NZ_AP021869:c1805271-1805011 [Vibrio gangliei]
ATGAAATTGACCTTTTCTAGTCACGCTTGGGAGGATTATTTATATTGGCAAAGTACAGATAAGAAGGTTCTCAAACGTAT
AAATTTATTAATTAAAGATATACAAAGAGAACCTTATGACGGGATTGGTAAGCCTGAGCCATTAAAGCATGGCTTGTCAG
GTTATTGGTCCCGGCGAATTAATGATGAGCACCGAATCGTTTATCGCTATCACGACAATACGATTCTTATTGCTCAACTT
CGTTTTCATTACGGTTCCTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9212.46 Da        Isoelectric Point: 4.3351

>AT33390 WP_105903754.1 NZ_AP021869:c1805519-1805268 [Vibrio gangliei]
MDAISYTAARANLASTMEKVCADHAPVIITRKSEAPVVMISLEDYEAMQETTYLLRAPTNARRLLESIAELESGQGQERE
LLE

Download         Length: 252 bp

>AT33390 NZ_AP021869:c1805519-1805268 [Vibrio gangliei]
ATGGACGCAATTAGTTATACCGCGGCTCGCGCAAATTTGGCGAGTACGATGGAAAAAGTCTGTGCTGATCATGCTCCGGT
GATCATCACCCGTAAAAGTGAAGCGCCTGTTGTGATGATTTCACTGGAAGATTATGAAGCGATGCAAGAGACCACCTACT
TGCTTCGAGCCCCAACCAATGCTCGACGTTTATTGGAGTCAATTGCTGAACTTGAATCTGGACAAGGACAAGAAAGGGAA
TTACTTGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References