33372

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 719645..721374 Replicon chromosome
Accession NZ_AP020337
Organism Pseudomonas sp. KUIN-1

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag KUIN1_RS03385 Protein ID WP_024650729.1
Coordinates 720730..721374 (-) Length 215 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag KUIN1_RS03380 Protein ID WP_116886429.1
Coordinates 719645..720733 (-) Length 363 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KUIN1_RS03350 714805..715125 + 321 WP_004407887.1 hypothetical protein -
KUIN1_RS03355 715128..716903 + 1776 WP_116886433.1 hypothetical protein -
KUIN1_RS03360 716900..717505 + 606 WP_032657102.1 hypothetical protein -
KUIN1_RS03365 717560..718603 + 1044 WP_024660348.1 LPS biosynthesis protein -
KUIN1_RS03370 718635..718880 - 246 WP_004407900.1 helix-turn-helix domain-containing protein -
KUIN1_RS03375 719002..719346 + 345 WP_116886431.1 hypothetical protein -
KUIN1_RS03380 719645..720733 - 1089 WP_116886429.1 macro domain-containing protein Antitoxin
KUIN1_RS03385 720730..721374 - 645 WP_024650729.1 DUF4433 domain-containing protein Toxin
KUIN1_RS03390 721371..721760 - 390 WP_116886428.1 DUF4433 domain-containing protein -
KUIN1_RS03395 722054..722785 - 732 WP_004409537.1 helix-turn-helix transcriptional regulator -
KUIN1_RS03400 723138..723665 - 528 WP_003317259.1 inorganic diphosphatase -
KUIN1_RS03405 723776..724585 - 810 WP_116886427.1 zinc-dependent peptidase -
KUIN1_RS03410 724589..725236 - 648 WP_116886426.1 DedA family protein -
KUIN1_RS03415 725478..726326 - 849 WP_172980034.1 ethanolamine ammonia-lyase subunit EutC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(14-213)

Antitoxin

Macro domain

(18-130)


Sequences

Toxin        


Download         Length: 215 a.a.        Molecular weight: 24814.21 Da        Isoelectric Point: 6.4934

>T33372 WP_024650729.1 NZ_AP020337:c721374-720730 [Pseudomonas sp. KUIN-1]
MIYRSLNPEKALIWRIVHRDNLPWILDNGLHCASSDVQAPYYVNIGNTDLIDKRRNRVVPIAPGGVLSDYVPFYFTPFSV
MMKNIQSGWSVQQRSNEEIVILVSSLPRAEHLGLAFVFTNAHAYPDWTDYYSDLADLDRVDWSIIQRRDFKRDADDPRRM
ERYQAEALIHHHLPITGLLGIMCYDDATKERIEQDVAARGLTLPVHARPGWYFQ

Download         Length: 645 bp

>T33372 NZ_AP020337:c721374-720730 [Pseudomonas sp. KUIN-1]
ATGATTTATCGCAGTCTGAATCCAGAAAAAGCTCTGATTTGGCGGATCGTCCATCGCGATAATCTGCCCTGGATTCTGGA
TAACGGCCTACATTGCGCCAGCTCCGACGTGCAGGCACCGTATTATGTGAACATCGGCAACACCGACCTGATCGACAAAC
GCCGCAACCGCGTTGTTCCCATTGCTCCCGGGGGCGTATTGTCTGACTACGTGCCGTTCTACTTCACACCTTTCTCTGTG
ATGATGAAAAACATCCAGTCCGGGTGGAGCGTTCAGCAGCGTAGCAATGAAGAGATAGTGATTCTGGTCTCAAGCCTTCC
CCGCGCCGAACATCTCGGTCTCGCTTTCGTCTTCACCAACGCACATGCCTATCCCGACTGGACCGACTACTACAGCGATC
TGGCAGATCTTGACCGGGTCGACTGGTCTATAATCCAGCGACGCGATTTCAAGCGCGATGCTGATGATCCACGTAGGATG
GAGCGTTATCAGGCCGAAGCGCTCATTCACCATCACCTACCGATCACAGGACTCCTTGGCATCATGTGCTACGACGATGC
AACGAAAGAACGTATTGAGCAAGACGTTGCCGCCAGAGGTCTGACCTTGCCTGTCCACGCGCGCCCGGGATGGTATTTCC
AATGA

Antitoxin


Download         Length: 363 a.a.        Molecular weight: 40415.39 Da        Isoelectric Point: 6.2609

>AT33372 WP_116886429.1 NZ_AP020337:c720733-719645 [Pseudomonas sp. KUIN-1]
MIRFTQGNLLEADTEALVNTVNTVGVMGKGIALMFKERFTENYRLYSAACKAGEVETGKVHVTAVNELDGPRWIVNFPTK
RHWRSPSQMAWITEGLRDLRRFLIDNQVKSVAVPPLGAGNGGLKWVEVREQIVDVLSNLDVDVLVFEPTDQYLNVAKRSG
VEKLTPARALIAELVRRYWVLGMECSLLEIQKLAWFLERSIEQLPSAKNPLDLKFVAHKYGPYANRLEHLLDNLDGSYLH
CDKRISDAGINDVIWFDEGRKAFLQTYLKTEAKEYSQALECTAELIDGFESPFGMELLATVDWLLSKSGVSPTVPAVREA
LKHWDGGAGAAARKSRLFDDQALGIALKRLTASNLSPEIAAP

Download         Length: 1089 bp

>AT33372 NZ_AP020337:c720733-719645 [Pseudomonas sp. KUIN-1]
ATGATCAGATTCACCCAAGGCAATCTGCTGGAAGCAGATACCGAAGCTCTCGTGAACACGGTGAACACGGTAGGCGTGAT
GGGAAAAGGCATTGCACTGATGTTCAAGGAGCGCTTTACCGAAAACTACCGCCTCTATTCGGCGGCGTGCAAGGCTGGTG
AGGTAGAGACCGGAAAGGTTCACGTAACGGCAGTCAACGAACTGGACGGGCCGCGCTGGATAGTGAATTTTCCTACCAAG
CGTCACTGGCGTTCCCCCTCGCAGATGGCATGGATAACTGAAGGCTTACGGGACCTGCGCCGCTTTTTGATCGATAACCA
AGTCAAATCCGTAGCAGTTCCACCTCTCGGTGCTGGTAATGGCGGTTTGAAATGGGTAGAGGTCCGTGAGCAGATTGTTG
ATGTCTTGAGTAATCTGGATGTCGATGTACTTGTCTTTGAACCTACCGATCAATATCTGAATGTCGCGAAGCGCAGCGGT
GTCGAGAAGCTGACGCCTGCACGTGCACTCATCGCCGAACTCGTTCGGCGTTACTGGGTTTTGGGCATGGAATGTAGCCT
GCTTGAAATTCAGAAGCTCGCTTGGTTTCTGGAGCGTTCGATAGAACAATTGCCAAGCGCAAAGAACCCCTTGGATCTCA
AATTTGTAGCCCACAAATATGGGCCATACGCCAATCGCCTTGAGCATCTGCTCGACAATCTCGATGGCAGCTACCTGCAT
TGCGATAAACGCATCAGCGACGCAGGTATTAACGACGTGATCTGGTTTGACGAGGGCCGTAAGGCTTTTCTGCAAACCTA
TCTGAAAACAGAGGCCAAGGAATATTCCCAAGCCCTGGAGTGCACAGCAGAGCTGATTGACGGCTTTGAGTCGCCTTTCG
GCATGGAGCTGTTGGCGACGGTTGACTGGTTATTGAGTAAGTCGGGAGTTTCTCCAACGGTTCCGGCAGTGCGCGAAGCA
TTGAAACATTGGGATGGAGGCGCAGGTGCGGCGGCTCGGAAAAGCAGGCTGTTCGACGATCAAGCTCTCGGCATTGCGTT
AAAGCGGTTGACTGCTAGCAATCTCAGTCCAGAGATAGCCGCCCCCTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References