Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Rv0298-Rv0299/-
Location 718790..719295 Replicon chromosome
Accession NZ_AP020326
Organism Mycobacterium avium subsp. hominissuis strain JP-H-1

Toxin (Protein)


Gene name Rv0299 Uniprot ID X7VD93
Locus tag JPH1_RS03635 Protein ID WP_007172144.1
Coordinates 718790..719095 (-) Length 102 a.a.

Antitoxin (Protein)


Gene name Rv0298 Uniprot ID -
Locus tag JPH1_RS03640 Protein ID WP_151834792.1
Coordinates 719092..719295 (-) Length 68 a.a.

Genomic Context

JPH1_RS27220JPH1_RS03610JPH1_RS03615JPH1_RS03620JPH1_RS03625JPH1_RS27225JPH1_RS03650JPH1_RS03655JPH1_RS03635JPH1_RS03640
Location: 713868..714008 (141 bp)
Type: Others
Protein ID: WP_007172137.1
Location: 714005..714391 (387 bp)
Type: Others
Protein ID: WP_007172138.1
Location: 714461..715138 (678 bp)
Type: Others
Protein ID: WP_101930854.1
Location: 715138..715470 (333 bp)
Type: Others
Protein ID: WP_033717256.1
Location: 715758..716045 (288 bp)
Type: Others
Protein ID: WP_007172141.1
Location: 716064..718418 (2355 bp)
Type: Others
Protein ID: WP_007172142.1
Location: 719805..721295 (1491 bp)
Type: Others
Protein ID: WP_007172147.1
Location: 721369..722424 (1056 bp)
Type: Others
Protein ID: WP_007172148.1
Location: 718790..719095 (306 bp)
Type: Toxin
Protein ID: WP_007172144.1
Location: 719092..719295 (204 bp)
Type: Antitoxin
Protein ID: WP_151834792.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
JPH1_RS27220713868..714008+141WP_007172137.1hypothetical protein-
JPH1_RS03610714005..714391+387WP_007172138.1YbaB/EbfC family nucleoid-associated protein-
JPH1_RS03615714461..715138+678WP_101930854.1hypothetical protein-
JPH1_RS03620715138..715470+333WP_033717256.1hypothetical protein-
JPH1_RS03625715758..716045+288WP_007172141.1hypothetical protein-
JPH1_RS27225716064..718418+2355WP_007172142.1hypothetical protein-
JPH1_RS03635718790..719095-306WP_007172144.1hypothetical proteinToxin
JPH1_RS03640719092..719295-204WP_151834792.1antitoxinAntitoxin
JPH1_RS03650719805..721295+1491WP_007172147.1type VII secretion protein EccB-
JPH1_RS03655721369..722424+1056WP_007172148.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Ribbon-helix-helix protein, CopG

(3-33)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 10428.23 Da        Isoelectric Point: 3.9382

>T33360 WP_007172144.1 NZ_AP020326:c719095-718790 [Mycobacterium avium subsp. hominissuis]
VITPGDITPGRDTNQELYVVVLSNTIHLAAATGQVIICPFIPGEIPSSTMAMIVTVLQPKGVVLPELIQWLPVAALDQPI
GNIGGIALADTTTTAVTALIS

Download         Length: 306 bp

>T33360 NZ_AP020326:c719095-718790 [Mycobacterium avium subsp. hominissuis]
GTGATCACACCCGGAGACATCACGCCAGGCCGCGACACCAACCAGGAACTGTACGTTGTCGTACTATCTAACACGATTCA
CCTCGCAGCCGCCACCGGCCAGGTGATCATCTGCCCCTTCATTCCCGGTGAAATCCCCAGCAGCACAATGGCTATGATCG
TCACAGTGCTGCAACCCAAAGGGGTTGTCTTACCGGAGCTCATCCAGTGGCTTCCTGTCGCGGCCCTCGACCAACCCATC
GGCAATATCGGCGGCATCGCGCTCGCTGACACGACCACGACCGCCGTCACCGCGCTCATTTCCTGA

Antitoxin


Download         Length: 68 a.a.        Molecular weight: 7338.17 Da        Isoelectric Point: 4.4760

>AT33360 WP_151834792.1 NZ_AP020326:c719295-719092 [Mycobacterium avium subsp. hominissuis]
MIEEAVLAAADADAQAAGLNRSEMIERALHNEHLRISLENYTTHTVPTLDIDAYAEKVYQANRAAGL

Download         Length: 204 bp

>AT33360 NZ_AP020326:c719295-719092 [Mycobacterium avium subsp. hominissuis]
ATGATTGAAGAGGCCGTGCTGGCGGCGGCCGATGCGGACGCCCAGGCGGCCGGGCTGAATCGTTCAGAGATGATCGAACG
AGCCCTGCACAACGAGCATCTCCGAATCTCGCTCGAGAACTACACAACACACACTGTGCCAACGCTCGACATCGACGCCT
ACGCGGAGAAGGTCTATCAGGCGAACCGGGCCGCTGGCCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A1X1XDZ0

Antitoxin

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Source
ID
Structure
No matching records found

References