Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-DinJ
Location 1192132..1192708 Replicon chromosome
Accession NZ_AP019835
Organism Leptotrichia wadei strain JMUB3934

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FVE76_RS05720 Protein ID WP_146964336.1
Coordinates 1192132..1192428 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FVE76_RS05725 Protein ID WP_146964337.1
Coordinates 1192418..1192708 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FVE76_RS05690 1187841..1188356 - 516 WP_060918037.1 galactose-6-phosphate isomerase subunit LacB -
FVE76_RS05695 1188406..1188828 - 423 WP_060918038.1 galactose-6-phosphate isomerase subunit LacA -
FVE76_RS05700 1189142..1189900 - 759 WP_146964333.1 DeoR/GlpR family DNA-binding transcription regulator -
FVE76_RS05705 1190065..1190256 - 192 WP_146960708.1 hypothetical protein -
FVE76_RS05710 1190314..1191045 - 732 WP_146964334.1 YaaA family protein -
FVE76_RS05715 1191049..1192053 - 1005 WP_146964335.1 class 1b ribonucleoside-diphosphate reductase subunit beta -
FVE76_RS05720 1192132..1192428 - 297 WP_146964336.1 type II toxin-antitoxin system YafQ family toxin Toxin
FVE76_RS05725 1192418..1192708 - 291 WP_146964337.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
FVE76_RS05730 1192782..1193726 - 945 WP_146964338.1 Abi family protein -
FVE76_RS05735 1194101..1195294 - 1194 WP_146964339.1 hypothetical protein -
FVE76_RS05740 1195532..1195987 - 456 WP_146964340.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(12-98)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-87)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11443.66 Da        Isoelectric Point: 10.0837

>T33164 WP_146964336.1 NZ_AP019835:c1192428-1192132 [Leptotrichia wadei]
MKGKKEEYKYSIILTGKFKKHLKNLKKQKKDLKLLESIISILAKGEKLPPKNKDHKLINNYDEARECHITPVWLLIYEIV
EDKLILILLASGSHSELF

Download         Length: 297 bp

>T33164 NZ_AP019835:c1192428-1192132 [Leptotrichia wadei]
ATGAAGGGTAAAAAAGAAGAGTATAAATATTCTATTATTCTTACTGGGAAATTTAAAAAACATTTAAAAAATCTAAAAAA
ACAGAAAAAAGATTTAAAATTATTAGAAAGTATAATCTCAATATTAGCAAAAGGAGAAAAACTTCCTCCTAAAAACAAAG
ATCATAAATTAATCAATAATTATGATGAGGCAAGAGAATGTCATATAACTCCAGTTTGGTTATTAATCTACGAGATAGTT
GAAGATAAATTAATATTGATTTTATTAGCATCAGGTAGTCATAGTGAACTATTCTAA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10881.32 Da        Isoelectric Point: 4.7049

>AT33164 WP_146964337.1 NZ_AP019835:c1192708-1192418 [Leptotrichia wadei]
MATVNTSIKIDEKTKKEAQELFKDLGLSLSTAINIFLKQAIREKGIPFYINSLPENSELAQAFEEAKQIKKNPSNYKSYS
SPEEMFKDVLGEDYEG

Download         Length: 291 bp

>AT33164 NZ_AP019835:c1192708-1192418 [Leptotrichia wadei]
ATGGCAACAGTTAATACAAGTATAAAGATAGATGAGAAAACTAAAAAAGAAGCACAGGAATTATTTAAAGATTTAGGATT
AAGTCTTAGTACAGCAATTAATATATTTTTGAAACAAGCTATAAGAGAAAAAGGCATACCATTTTATATAAATTCTTTAC
CTGAAAATTCAGAATTGGCTCAAGCATTTGAAGAAGCCAAACAAATTAAGAAAAATCCTTCAAATTATAAATCGTACAGT
AGTCCAGAAGAAATGTTTAAAGATGTCTTGGGAGAAGATTATGAAGGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References