Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-RelB
Location 1596565..1597078 Replicon chromosome
Accession NZ_AP019822
Organism Pseudoleptotrichia goodfellowii strain JCM16774

Toxin (Protein)


Gene name yoeB Uniprot ID D0GJ08
Locus tag FVE72_RS07810 Protein ID WP_006806445.1
Coordinates 1596565..1596819 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID D0GJ07
Locus tag FVE72_RS07815 Protein ID WP_006806440.1
Coordinates 1596821..1597078 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FVE72_RS07795 1591644..1592522 + 879 WP_026737902.1 sugar ABC transporter permease -
FVE72_RS07800 1592526..1593356 + 831 WP_026737903.1 carbohydrate ABC transporter permease -
FVE72_RS07805 1593360..1596497 + 3138 WP_026737904.1 DUF4981 domain-containing protein -
FVE72_RS07810 1596565..1596819 - 255 WP_006806445.1 Txe/YoeB family addiction module toxin Toxin
FVE72_RS07815 1596821..1597078 - 258 WP_006806440.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
FVE72_RS07820 1597221..1597901 - 681 WP_026737905.1 hypothetical protein -
FVE72_RS07825 1598064..1598576 - 513 WP_006806430.1 hypothetical protein -
FVE72_RS07830 1598610..1599053 - 444 WP_006806429.1 hypothetical protein -
FVE72_RS07835 1599081..1599674 - 594 WP_006806465.1 hypothetical protein -
FVE72_RS07840 1599780..1600256 - 477 WP_026737906.1 hypothetical protein -
FVE72_RS07845 1600349..1601281 - 933 WP_026737907.1 hypothetical protein -
FVE72_RS07850 1601297..1601659 - 363 WP_051411770.1 PepSY domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10176.65 Da        Isoelectric Point: 8.9147

>T33144 WP_006806445.1 NZ_AP019822:c1596819-1596565 [Pseudoleptotrichia goodfellowii]
MKISWNNKAWEEYVKWQSEDKKVVKKINELIKDIERNGNEGIGKPEPLKHEFSGFWSRRITDKHRFIYRITEEEIIIIAC
ANHY

Download         Length: 255 bp

>T33144 NZ_AP019822:c1596819-1596565 [Pseudoleptotrichia goodfellowii]
ATGAAAATAAGTTGGAATAATAAAGCATGGGAAGAATATGTAAAATGGCAGTCTGAAGATAAAAAGGTTGTTAAGAAAAT
AAATGAGCTGATAAAAGATATAGAAAGAAACGGAAACGAGGGGATAGGGAAGCCGGAGCCTTTAAAACATGAATTTAGCG
GATTTTGGAGCAGAAGAATAACCGATAAGCATAGATTTATATACAGAATTACCGAAGAGGAAATTATAATAATAGCTTGT
GCAAATCATTATTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10061.33 Da        Isoelectric Point: 4.3535

>AT33144 WP_006806440.1 NZ_AP019822:c1597078-1596821 [Pseudoleptotrichia goodfellowii]
MIAVNYSSARNNFKDYCDKATDDFETIIITRKENKNVVLMSEDEYNNLMENLYIMSNKKYYNELLKRKAEVEAGLVEEHD
IIEVE

Download         Length: 258 bp

>AT33144 NZ_AP019822:c1597078-1596821 [Pseudoleptotrichia goodfellowii]
ATGATAGCTGTAAATTATTCAAGTGCAAGAAATAACTTTAAAGATTATTGCGACAAAGCGACTGACGACTTTGAAACAAT
CATTATAACAAGAAAAGAAAATAAAAATGTCGTTTTAATGAGTGAAGACGAGTATAATAATCTTATGGAAAATCTTTATA
TTATGTCGAATAAGAAATATTATAACGAATTACTTAAAAGAAAAGCGGAAGTGGAAGCGGGGTTAGTGGAAGAACACGAT
ATAATTGAGGTGGAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A510JE26

Antitoxin

Source ID Structure
AlphaFold DB A0A510JBK9

References