Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/RelE-RelB |
| Location | 1936691..1937250 | Replicon | chromosome |
| Accession | NZ_AP019798 | ||
| Organism | Vibrio rotiferianus strain AM7 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | A0A347UR22 |
| Locus tag | VroAM7_RS09075 | Protein ID | WP_005398411.1 |
| Coordinates | 1936972..1937250 (+) | Length | 93 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | A0A347UR21 |
| Locus tag | VroAM7_RS09070 | Protein ID | WP_005398409.1 |
| Coordinates | 1936691..1936975 (+) | Length | 95 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| VroAM7_RS09015 | 1932328..1932420 | - | 93 | WP_143692584.1 | DUF3265 domain-containing protein | - |
| VroAM7_RS09020 | 1932435..1932998 | - | 564 | WP_143692585.1 | hypothetical protein | - |
| VroAM7_RS09025 | 1933146..1933592 | - | 447 | WP_143692586.1 | hypothetical protein | - |
| VroAM7_RS09030 | 1933594..1933899 | - | 306 | WP_143692587.1 | DUF4325 domain-containing protein | - |
| VroAM7_RS09035 | 1933896..1934459 | - | 564 | WP_143692588.1 | hypothetical protein | - |
| VroAM7_RS09040 | 1934623..1935126 | - | 504 | WP_143692589.1 | peptide deformylase | - |
| VroAM7_RS09045 | 1935164..1935256 | - | 93 | WP_005445734.1 | DUF3265 domain-containing protein | - |
| VroAM7_RS09050 | 1935288..1935716 | - | 429 | WP_053397211.1 | GNAT family N-acetyltransferase | - |
| VroAM7_RS09055 | 1935752..1935844 | - | 93 | WP_197737453.1 | DUF3265 domain-containing protein | - |
| VroAM7_RS09060 | 1935859..1936494 | - | 636 | WP_045594167.1 | hypothetical protein | - |
| VroAM7_RS09065 | 1936523..1936614 | - | 92 | Protein_1698 | DUF3265 domain-containing protein | - |
| VroAM7_RS09070 | 1936691..1936975 | + | 285 | WP_005398409.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
| VroAM7_RS09075 | 1936972..1937250 | + | 279 | WP_005398411.1 | type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family | Toxin |
| VroAM7_RS09080 | 1937396..1938379 | - | 984 | WP_052699596.1 | hypothetical protein | - |
| VroAM7_RS09085 | 1938407..1938541 | - | 135 | WP_143693230.1 | DUF3265 domain-containing protein | - |
| VroAM7_RS09090 | 1938514..1938939 | - | 426 | WP_107279085.1 | hypothetical protein | - |
| VroAM7_RS09095 | 1939088..1939486 | - | 399 | WP_143692590.1 | hypothetical protein | - |
| VroAM7_RS27295 | 1939514..1939605 | - | 92 | Protein_1705 | DUF3265 domain-containing protein | - |
| VroAM7_RS09105 | 1939620..1940093 | - | 474 | WP_143692591.1 | hypothetical protein | - |
| VroAM7_RS09110 | 1940123..1940212 | - | 90 | WP_197737457.1 | DUF3265 domain-containing protein | - |
| VroAM7_RS09115 | 1940236..1940754 | - | 519 | WP_143692592.1 | hypothetical protein | - |
| VroAM7_RS09120 | 1941041..1941133 | - | 93 | WP_006074995.1 | DUF3265 domain-containing protein | - |
| VroAM7_RS09125 | 1941161..1942087 | - | 927 | WP_143692593.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Integrative and Conjugative Element | - | VP1611 | 1711712..2127777 | 416065 | |
| - | inside | Integron | - | - | 1889467..1947985 | 58518 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 93 a.a. Molecular weight: 10891.57 Da Isoelectric Point: 4.3430
>T33075 WP_005398411.1 NZ_AP019798:1936972-1937250 [Vibrio rotiferianus]
MILWEEESLNDREKIFEFLYDFNPDAAEKTDNLIEAKVENLLEQPLMGVQRDGIRGRLLIIPEISMIVSYWVEGDIIRVM
RVLHQKQKFPTD
MILWEEESLNDREKIFEFLYDFNPDAAEKTDNLIEAKVENLLEQPLMGVQRDGIRGRLLIIPEISMIVSYWVEGDIIRVM
RVLHQKQKFPTD
Download Length: 279 bp
>T33075 NZ_AP019798:1936972-1937250 [Vibrio rotiferianus]
ATGATTTTATGGGAAGAAGAGTCACTTAATGATCGTGAAAAGATCTTCGAGTTTCTCTATGACTTCAACCCTGATGCGGC
AGAAAAAACTGACAACCTCATTGAAGCAAAAGTAGAAAACTTGCTTGAACAACCTTTGATGGGTGTACAACGAGATGGCA
TCCGCGGACGATTGCTCATTATTCCTGAGATTTCGATGATTGTCTCTTACTGGGTCGAGGGCGATATCATCAGAGTTATG
CGTGTACTCCACCAGAAACAAAAATTCCCTACGGATTGA
ATGATTTTATGGGAAGAAGAGTCACTTAATGATCGTGAAAAGATCTTCGAGTTTCTCTATGACTTCAACCCTGATGCGGC
AGAAAAAACTGACAACCTCATTGAAGCAAAAGTAGAAAACTTGCTTGAACAACCTTTGATGGGTGTACAACGAGATGGCA
TCCGCGGACGATTGCTCATTATTCCTGAGATTTCGATGATTGTCTCTTACTGGGTCGAGGGCGATATCATCAGAGTTATG
CGTGTACTCCACCAGAAACAAAAATTCCCTACGGATTGA
Antitoxin
Download Length: 95 a.a. Molecular weight: 11069.40 Da Isoelectric Point: 9.2167
>AT33075 WP_005398409.1 NZ_AP019798:1936691-1936975 [Vibrio rotiferianus]
MDTRIQFRVDEETKRLAQQMAESQGRTLSDACRELTEQLAEQQRKTLSHDAWLTEQVNLAFEKFDSGKSVFVEHQTAKSR
MEERKARIRNRGKQ
MDTRIQFRVDEETKRLAQQMAESQGRTLSDACRELTEQLAEQQRKTLSHDAWLTEQVNLAFEKFDSGKSVFVEHQTAKSR
MEERKARIRNRGKQ
Download Length: 285 bp
>AT33075 NZ_AP019798:1936691-1936975 [Vibrio rotiferianus]
ATGGACACTAGAATTCAATTTCGTGTTGATGAAGAAACAAAACGCCTAGCTCAACAAATGGCTGAGAGCCAAGGTCGAAC
TCTAAGTGATGCTTGCCGTGAACTTACTGAGCAACTCGCTGAACAACAAAGAAAAACATTATCTCACGATGCATGGCTAA
CTGAACAAGTAAACCTAGCATTTGAGAAGTTTGACTCAGGAAAGTCTGTTTTCGTTGAGCACCAAACTGCTAAGTCTCGA
ATGGAAGAGCGCAAAGCCAGAATCCGTAATCGAGGTAAGCAATGA
ATGGACACTAGAATTCAATTTCGTGTTGATGAAGAAACAAAACGCCTAGCTCAACAAATGGCTGAGAGCCAAGGTCGAAC
TCTAAGTGATGCTTGCCGTGAACTTACTGAGCAACTCGCTGAACAACAAAGAAAAACATTATCTCACGATGCATGGCTAA
CTGAACAAGTAAACCTAGCATTTGAGAAGTTTGACTCAGGAAAGTCTGTTTTCGTTGAGCACCAAACTGCTAAGTCTCGA
ATGGAAGAGCGCAAAGCCAGAATCCGTAATCGAGGTAAGCAATGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A347UR22 |
Antitoxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A347UR21 |