Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/RelE-RelB |
| Location | 1925559..1926118 | Replicon | chromosome |
| Accession | NZ_AP019798 | ||
| Organism | Vibrio rotiferianus strain AM7 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | A0A2K7SRU8 |
| Locus tag | VroAM7_RS08930 | Protein ID | WP_017035198.1 |
| Coordinates | 1925840..1926118 (+) | Length | 93 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | - |
| Locus tag | VroAM7_RS08925 | Protein ID | WP_138941952.1 |
| Coordinates | 1925559..1925843 (+) | Length | 95 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| VroAM7_RS08875 | 1921232..1921324 | - | 93 | WP_079765077.1 | DUF3265 domain-containing protein | - |
| VroAM7_RS08880 | 1921339..1921848 | - | 510 | WP_017048678.1 | ClbS/DfsB family four-helix bundle protein | - |
| VroAM7_RS08885 | 1921876..1921968 | - | 93 | WP_197737451.1 | DUF3265 domain-containing protein | - |
| VroAM7_RS08890 | 1921997..1922812 | - | 816 | WP_138942017.1 | hypothetical protein | - |
| VroAM7_RS27275 | 1922866..1922958 | - | 93 | WP_005537214.1 | DUF3265 domain-containing protein | - |
| VroAM7_RS08900 | 1922973..1923365 | - | 393 | WP_033000829.1 | hypothetical protein | - |
| VroAM7_RS08905 | 1923522..1924160 | - | 639 | WP_172622552.1 | signal peptidase I | - |
| VroAM7_RS08910 | 1924254..1924346 | - | 93 | WP_079765597.1 | DUF3265 domain-containing protein | - |
| VroAM7_RS08915 | 1924361..1924849 | - | 489 | WP_143692576.1 | GNAT family N-acetyltransferase | - |
| VroAM7_RS08920 | 1925285..1925482 | - | 198 | WP_143692577.1 | DUF3265 domain-containing protein | - |
| VroAM7_RS08925 | 1925559..1925843 | + | 285 | WP_138941952.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
| VroAM7_RS08930 | 1925840..1926118 | + | 279 | WP_017035198.1 | type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family | Toxin |
| VroAM7_RS08935 | 1926147..1926239 | - | 93 | WP_074190183.1 | DUF3265 domain-containing protein | - |
| VroAM7_RS08940 | 1926254..1926871 | - | 618 | WP_143692578.1 | YdcF family protein | - |
| VroAM7_RS08950 | 1926967..1927713 | - | 747 | WP_143692579.1 | hypothetical protein | - |
| VroAM7_RS08955 | 1927886..1928443 | - | 558 | WP_143692580.1 | nucleotidyltransferase family protein | - |
| VroAM7_RS08960 | 1928464..1928586 | - | 123 | WP_080772513.1 | DUF3265 domain-containing protein | - |
| VroAM7_RS08965 | 1928571..1928855 | - | 285 | WP_143692581.1 | hypothetical protein | - |
| VroAM7_RS27280 | 1929063..1929332 | - | 270 | WP_197737452.1 | hypothetical protein | - |
| VroAM7_RS08975 | 1929364..1929456 | - | 93 | WP_194842422.1 | DUF3265 domain-containing protein | - |
| VroAM7_RS08980 | 1929471..1929959 | - | 489 | WP_071236582.1 | GNAT family N-acetyltransferase | - |
| VroAM7_RS08990 | 1930127..1930708 | - | 582 | WP_143692582.1 | hypothetical protein | - |
| VroAM7_RS27285 | 1930760..1930828 | - | 69 | WP_074531725.1 | DUF3265 domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Integrative and Conjugative Element | - | VP1611 | 1711712..2127777 | 416065 | |
| - | inside | Integron | - | - | 1889467..1947985 | 58518 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 93 a.a. Molecular weight: 10905.60 Da Isoelectric Point: 4.3430
>T33073 WP_017035198.1 NZ_AP019798:1925840-1926118 [Vibrio rotiferianus]
MILWEEESLNDREKIFEFLYDFNPDAAEKTDNLIEAKVENLLEQPLMGVQRDGIRGRLLIIPEISMIVSYWIEGDIIRVM
RVLHQKQKFPTD
MILWEEESLNDREKIFEFLYDFNPDAAEKTDNLIEAKVENLLEQPLMGVQRDGIRGRLLIIPEISMIVSYWIEGDIIRVM
RVLHQKQKFPTD
Download Length: 279 bp
>T33073 NZ_AP019798:1925840-1926118 [Vibrio rotiferianus]
ATGATTTTATGGGAAGAAGAGTCACTTAATGATCGTGAAAAGATCTTTGAGTTTCTCTATGACTTCAACCCTGATGCTGC
AGAAAAAACTGACAACCTCATTGAAGCAAAAGTAGAAAACTTGCTTGAACAACCTTTAATGGGGGTACAACGAGATGGCA
TCCGCGGACGATTACTCATCATTCCTGAGATTTCGATGATTGTCTCTTACTGGATTGAGGGCGATATCATCCGAGTTATG
CGTGTACTCCACCAGAAACAAAAATTCCCTACGGATTGA
ATGATTTTATGGGAAGAAGAGTCACTTAATGATCGTGAAAAGATCTTTGAGTTTCTCTATGACTTCAACCCTGATGCTGC
AGAAAAAACTGACAACCTCATTGAAGCAAAAGTAGAAAACTTGCTTGAACAACCTTTAATGGGGGTACAACGAGATGGCA
TCCGCGGACGATTACTCATCATTCCTGAGATTTCGATGATTGTCTCTTACTGGATTGAGGGCGATATCATCCGAGTTATG
CGTGTACTCCACCAGAAACAAAAATTCCCTACGGATTGA
Antitoxin
Download Length: 95 a.a. Molecular weight: 11097.41 Da Isoelectric Point: 9.2512
>AT33073 WP_138941952.1 NZ_AP019798:1925559-1925843 [Vibrio rotiferianus]
MDTRIQFRVDEETKRLAQQMAESQGRTLSDACRELTEQLAEQQRRTLSHDAWLTEQVNLAFEKFDSGKSVFVEHQTAKSR
MEERKARIRNRGKQ
MDTRIQFRVDEETKRLAQQMAESQGRTLSDACRELTEQLAEQQRRTLSHDAWLTEQVNLAFEKFDSGKSVFVEHQTAKSR
MEERKARIRNRGKQ
Download Length: 285 bp
>AT33073 NZ_AP019798:1925559-1925843 [Vibrio rotiferianus]
ATGGACACTAGAATTCAATTTCGTGTTGATGAAGAAACAAAACGCCTAGCTCAACAAATGGCTGAGAGCCAAGGTCGCAC
TCTGAGTGACGCATGTCGTGAACTTACTGAGCAACTCGCTGAACAACAAAGAAGAACATTATCTCACGATGCATGGCTAA
CTGAACAAGTAAACCTAGCATTTGAGAAGTTTGACTCAGGAAAATCCGTTTTCGTTGAGCACCAAACGGCTAAGTCTCGA
ATGGAAGAGCGCAAAGCCAGAATCCGTAATCGAGGTAAGCAATGA
ATGGACACTAGAATTCAATTTCGTGTTGATGAAGAAACAAAACGCCTAGCTCAACAAATGGCTGAGAGCCAAGGTCGCAC
TCTGAGTGACGCATGTCGTGAACTTACTGAGCAACTCGCTGAACAACAAAGAAGAACATTATCTCACGATGCATGGCTAA
CTGAACAAGTAAACCTAGCATTTGAGAAGTTTGACTCAGGAAAATCCGTTTTCGTTGAGCACCAAACGGCTAAGTCTCGA
ATGGAAGAGCGCAAAGCCAGAATCCGTAATCGAGGTAAGCAATGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|