Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /ElaA-DUF1778
Location 1916663..1917429 Replicon chromosome
Accession NZ_AP019798
Organism Vibrio rotiferianus strain AM7

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag VroAM7_RS08830 Protein ID WP_143692572.1
Coordinates 1916932..1917429 (+) Length 166 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag VroAM7_RS08825 Protein ID WP_143692571.1
Coordinates 1916663..1916935 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
VroAM7_RS08760 1911792..1912070 + 279 WP_143692564.1 type II toxin-antitoxin system RelE/ParE family toxin -
VroAM7_RS08765 1912227..1912595 - 369 WP_143692565.1 VOC family protein -
VroAM7_RS08770 1912643..1912735 - 93 WP_079400283.1 DUF3265 domain-containing protein -
VroAM7_RS08775 1912849..1913817 + 969 WP_143692547.1 IS30-like element ISVa6 family transposase -
VroAM7_RS08780 1913854..1914624 - 771 WP_172622550.1 FRG domain-containing protein -
VroAM7_RS08785 1914664..1914789 - 126 WP_143693220.1 DUF3265 domain-containing protein -
VroAM7_RS08790 1914786..1915157 - 372 WP_143692567.1 hypothetical protein -
VroAM7_RS08795 1915241..1915363 - 123 WP_143692568.1 DUF3265 domain-containing protein -
VroAM7_RS08800 1915360..1915644 - 285 WP_143692569.1 hypothetical protein -
VroAM7_RS08805 1915646..1915957 - 312 WP_143692570.1 hypothetical protein -
VroAM7_RS08810 1915984..1916076 - 93 WP_079858411.1 DUF3265 domain-containing protein -
VroAM7_RS08815 1916091..1916432 - 342 WP_172622548.1 hypothetical protein -
VroAM7_RS08825 1916663..1916935 + 273 WP_143692571.1 DUF1778 domain-containing protein Antitoxin
VroAM7_RS08830 1916932..1917429 + 498 WP_143692572.1 GNAT family N-acetyltransferase Toxin
VroAM7_RS08835 1917572..1918102 - 531 WP_143692573.1 hypothetical protein -
VroAM7_RS08840 1918130..1918222 - 93 WP_072612521.1 DUF3265 domain-containing protein -
VroAM7_RS08845 1918237..1918602 - 366 WP_172622551.1 hypothetical protein -
VroAM7_RS08850 1918584..1919063 - 480 WP_010448911.1 type VI secretion system amidase effector protein Tae4 -
VroAM7_RS08855 1919788..1919898 - 111 WP_086485322.1 DUF3265 domain-containing protein -
VroAM7_RS08860 1919904..1920248 - 345 WP_143692574.1 hypothetical protein -
VroAM7_RS08865 1920291..1920383 - 93 WP_078534682.1 DUF3265 domain-containing protein -
VroAM7_RS08870 1920411..1921193 - 783 WP_069538091.1 hypothetical protein -
VroAM7_RS08875 1921232..1921324 - 93 WP_079765077.1 DUF3265 domain-containing protein -
VroAM7_RS08880 1921339..1921848 - 510 WP_017048678.1 ClbS/DfsB family four-helix bundle protein -
VroAM7_RS08885 1921876..1921968 - 93 WP_197737451.1 DUF3265 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - VP1611 1711712..2127777 416065
- flank IS/Tn - - 1913041..1913817 776
- inside Integron - - 1889467..1947985 58518


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(85-148)

Antitoxin

Vibrio phage ICP1, Orf50

(7-86)


Sequences

Toxin        


Download         Length: 166 a.a.        Molecular weight: 18409.00 Da        Isoelectric Point: 8.7812

>T33072 WP_143692572.1 NZ_AP019798:1916932-1917429 [Vibrio rotiferianus]
MMNTVLLDKAKHDRNRFNCGTEALNNYLKVMASQQAKKDNTRTFVLEDESNEQHIIGFYTLTMTPIDLKALPAKLQKKHQ
SATSGGLIARLAVDDRYKGKGYGEWLLVDALRKLLAASDSVAFPVVVVDAKDGANQFYERYGFTAFQDADNKLFITISDV
RASLG

Download         Length: 498 bp

>T33072 NZ_AP019798:1916932-1917429 [Vibrio rotiferianus]
ATGATGAATACGGTACTTCTTGATAAAGCAAAACATGACAGAAACCGATTCAACTGCGGAACTGAAGCATTAAACAATTA
CTTAAAAGTAATGGCGAGTCAGCAAGCTAAAAAGGACAACACTAGAACATTTGTTTTGGAAGATGAAAGCAATGAACAGC
ATATCATTGGTTTTTATACGCTAACAATGACACCTATCGACTTGAAAGCTCTACCAGCAAAGCTACAAAAAAAGCACCAG
TCTGCCACATCTGGTGGTTTAATCGCTCGCTTAGCAGTAGATGACCGATACAAAGGCAAGGGTTACGGTGAATGGTTGCT
TGTCGATGCCCTAAGAAAACTACTCGCAGCGAGTGATAGTGTTGCTTTCCCTGTCGTAGTCGTTGACGCTAAAGATGGTG
CTAACCAATTTTACGAACGATATGGTTTTACTGCATTTCAGGACGCCGACAACAAGTTATTTATTACAATCTCTGATGTC
AGAGCGAGCTTAGGCTAG

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 9620.14 Da        Isoelectric Point: 9.8130

>AT33072 WP_143692571.1 NZ_AP019798:1916663-1916935 [Vibrio rotiferianus]
MATTLPRITARVDVDTQDLLTKAAAIAGMSSINSFVLSAAVEKAKQVIEREQALRLSQADAMLLMDALDKPASVNTKLKA
AASRYESKAQ

Download         Length: 273 bp

>AT33072 NZ_AP019798:1916663-1916935 [Vibrio rotiferianus]
ATGGCTACTACATTACCACGCATCACTGCTAGAGTTGATGTGGATACACAAGATTTGCTAACTAAAGCAGCCGCTATTGC
TGGAATGTCTAGCATTAACTCATTTGTTTTAAGTGCTGCCGTTGAAAAAGCAAAGCAAGTCATTGAACGTGAACAAGCAC
TCAGACTTAGTCAAGCAGATGCAATGCTACTTATGGACGCTCTCGATAAGCCTGCAAGTGTCAATACAAAGCTTAAAGCT
GCTGCAAGTCGTTATGAGAGCAAAGCTCAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References