Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 3551436..3551998 Replicon chromosome
Accession NZ_AP019782
Organism Methylogaea oryzae strain E10

Toxin (Protein)


Gene name vapC Uniprot ID A0A8D4VQ82
Locus tag K5607_RS15760 Protein ID WP_054774319.1
Coordinates 3551630..3551998 (+) Length 123 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A8D4VRN7
Locus tag K5607_RS15755 Protein ID WP_054774320.1
Coordinates 3551436..3551633 (+) Length 66 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K5607_RS15730 (MoryE10_30730) 3547370..3548218 + 849 WP_054774289.1 aldo/keto reductase -
K5607_RS15735 (MoryE10_30740) 3548282..3549124 - 843 WP_221047574.1 hypothetical protein -
K5607_RS15740 (MoryE10_30750) 3549121..3550173 - 1053 WP_221047575.1 MoxR family ATPase -
K5607_RS15745 (MoryE10_30760) 3550271..3550630 - 360 WP_217995070.1 hypothetical protein -
K5607_RS15750 (MoryE10_30770) 3550647..3551186 - 540 WP_054774322.1 SRPBCC family protein -
K5607_RS15755 (MoryE10_30780) 3551436..3551633 + 198 WP_054774320.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
K5607_RS15760 (MoryE10_30790) 3551630..3551998 + 369 WP_054774319.1 PIN domain-containing protein Toxin
K5607_RS15765 (MoryE10_30800) 3552005..3552955 - 951 WP_246598892.1 VWA domain-containing protein -
K5607_RS15770 (MoryE10_30810) 3553236..3553799 - 564 WP_246598893.1 MxaK protein -
K5607_RS15775 (MoryE10_30820) 3553810..3554790 - 981 WP_221047577.1 vWA domain-containing protein -
K5607_RS15780 (MoryE10_30830) 3554787..3555650 - 864 WP_221047578.1 nonribosomal peptide synthetase MxaA -
K5607_RS15785 (MoryE10_30840) 3555863..3556702 - 840 WP_246598894.1 VWA domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-111)

Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-43)


Sequences

Toxin        


Download         Length: 123 a.a.        Molecular weight: 13299.38 Da        Isoelectric Point: 6.6899

>T33056 WP_054774319.1 NZ_AP019782:3551630-3551998 [Methylogaea oryzae]
VILVDTSIWIDHFRGSGSVLSALLHTDHVCTHAWVIGELACGNLGNRAEILGLLQALPQLAPATAEEVLFFIERQRLMGR
GIGYVDVHLLAAAALHSSRLYTRDKRLHGIAEELGLAYPAVH

Download         Length: 369 bp

>T33056 NZ_AP019782:3551630-3551998 [Methylogaea oryzae]
GTGATCCTGGTTGACACGTCGATCTGGATCGACCATTTTCGCGGTTCCGGCAGCGTGCTATCGGCGCTGCTGCATACCGA
TCATGTTTGCACCCACGCCTGGGTCATCGGCGAATTGGCTTGCGGCAACCTGGGCAACCGCGCGGAAATCCTCGGCTTGT
TGCAAGCATTGCCGCAACTGGCCCCGGCCACGGCGGAGGAAGTGCTGTTTTTCATCGAACGGCAGCGGCTCATGGGGCGG
GGAATCGGCTACGTCGACGTGCATTTGCTCGCCGCCGCTGCGCTCCATTCCAGCCGGCTTTACACGCGGGACAAACGCTT
GCACGGCATCGCCGAAGAACTCGGCTTGGCTTATCCCGCCGTCCATTGA

Antitoxin


Download         Length: 66 a.a.        Molecular weight: 7054.06 Da        Isoelectric Point: 9.5216

>AT33056 WP_054774320.1 NZ_AP019782:3551436-3551633 [Methylogaea oryzae]
MRTTVTLDDALLAQAQALSGVQERSALLREALTALIQRESARRLAQLGGTEPALADIPRRRENGL

Download         Length: 198 bp

>AT33056 NZ_AP019782:3551436-3551633 [Methylogaea oryzae]
ATGCGAACCACGGTCACCCTGGACGATGCGCTGCTGGCCCAAGCCCAAGCCCTGAGCGGCGTGCAGGAGCGCAGCGCCTT
GTTGCGGGAAGCCCTGACGGCGCTGATTCAGCGGGAAAGCGCGCGCCGCTTGGCGCAATTGGGCGGGACGGAACCGGCGT
TGGCGGATATTCCCCGCCGGCGCGAGAACGGCTTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References