Detailed information of TA system TA033055

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-yefM/YoeB-RelB
• Location: 3135221..3135731
• Replicon: chromosome
• Accession: NZ_AP019782
• Organism: Methylogaea oryzae strain E10

Toxin (Protein)

• Gene name: relB
• Uniprot ID: A0A8D5ANH6
• Locus tag: K5607_RS13845
• Protein ID: WP_054772996.1
• Coordinates: 3135221..3135484 (-)
• Length: 88 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: -
• Locus tag: K5607_RS13850
• Protein ID: WP_221047363.1
• Coordinates: 3135477..3135731 (-)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
K5607_RS13830 (MoryE10_27080)	3133245..3133709	+	465	WP_054772993.1	GyrI-like domain-containing protein	-
K5607_RS13835 (MoryE10_27090)	3133874..3134233	+	360	WP_054772994.1	hypothetical protein	-
K5607_RS13840 (MoryE10_27100)	3134618..3134992	+	375	WP_054772995.1	hypothetical protein	-
K5607_RS13845 (MoryE10_27110)	3135221..3135484	-	264	WP_054772996.1	Txe/YoeB family addiction module toxin	Toxin
K5607_RS13850 (MoryE10_27120)	3135477..3135731	-	255	WP_221047363.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
K5607_RS13855 (MoryE10_27130)	3135779..3137161	-	1383	WP_054772997.1	ATP-dependent RNA helicase DbpA	-
K5607_RS13860 (MoryE10_27140)	3137425..3137790	-	366	WP_082411384.1	small metal-binding protein SmbP	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (4-86)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-74)

Sequences

Toxin

Protein

• Length: 88 a.a.
• Molecular weight: 10404.80 Da
• Isoelectric Point: 7.8164

>T33055 WP_054772996.1 NZ_AP019782:c3135484-3135221 [Methylogaea oryzae]
MPSRITWTLAAREDYQYWQGQDRKTLKRINGLIQDCLREPFDGIGKPEPLKENLSGFWSRRIDETHRLVYRVDGDDLVVI
ACRYRYD

Nucleotide

• Length: 264 bp

>T33055 NZ_AP019782:c3135484-3135221 [Methylogaea oryzae]
ATGCCTAGCCGCATCACCTGGACTTTGGCCGCCCGGGAAGACTACCAATACTGGCAAGGACAGGATCGCAAGACCCTGAA
GCGGATCAACGGCCTGATCCAAGACTGCCTGCGCGAACCCTTCGACGGCATCGGCAAGCCGGAGCCCCTCAAGGAAAACC
TGTCCGGCTTTTGGTCGCGCCGTATCGATGAAACCCATCGTCTGGTTTATCGAGTCGATGGCGACGATTTGGTCGTTATT
GCTTGCCGTTATCGCTACGACTAA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9472.71 Da
• Isoelectric Point: 5.0041

>AT33055 WP_221047363.1 NZ_AP019782:c3135731-3135477 [Methylogaea oryzae]
MRVINFSEARNNLKNVIDQVIDDADYTVIARRDAPDAVMMSLDTFNSLMETVHLLKSPANAAHLARSIEQYRQGKLTEQN
PIDA

Nucleotide

• Length: 255 bp

>AT33055 NZ_AP019782:c3135731-3135477 [Methylogaea oryzae]
ATGCGCGTAATAAATTTTTCCGAGGCCCGAAACAACCTCAAGAACGTCATCGATCAGGTCATCGACGATGCCGATTACAC
CGTGATCGCCCGGCGCGACGCGCCCGACGCAGTCATGATGTCGCTCGACACGTTCAACAGCCTGATGGAGACCGTCCACC
TGCTGAAGTCTCCCGCCAATGCCGCCCATCTGGCCCGCTCCATTGAGCAATACCGCCAGGGCAAGTTGACCGAGCAAAAT
CCGATCGATGCCTAG