Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2270221..2270492 Replicon chromosome
Accession NZ_AP019761
Organism Escherichia coli O111:H- strain 110512

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2270259..2270362 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2270221..2270492 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EC110512_RS11670 2267378..2268817 + 1440 WP_000057021.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
EC110512_RS11675 2268935..2269171 + 237 WP_001295499.1 DUF1480 family protein -
EC110512_RS11680 2269276..2269467 + 192 WP_001296140.1 YebW family protein -
EC110512_RS11685 2269468..2270124 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 2270221..2270492 + 272 - - Antitoxin
- 2270259..2270362 - 104 - - Toxin
EC110512_RS11690 2270520..2270861 - 342 WP_000976492.1 YebY family protein -
EC110512_RS11695 2270874..2271746 - 873 WP_000879274.1 copper homeostasis membrane protein CopD -
EC110512_RS11700 2271750..2272124 - 375 WP_000204699.1 CopC domain-containing protein YobA -
EC110512_RS11705 2272263..2272493 + 231 WP_000916763.1 DNA polymerase III subunit theta -
EC110512_RS11710 2272595..2273251 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
EC110512_RS11715 2273275..2273937 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T33017 NZ_AP019761:c2270362-2270259 [Escherichia coli O111:H-]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT33017 NZ_AP019761:2270221-2270492 [Escherichia coli O111:H-]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References